1887

Abstract

SUMMARY

We and others have previously shown that a mutant in herpes simplex virus type 1 (HSV-1) complementation group 1–4 induces a virus-specified DNA polymerase that is temperature-sensitive . Here we report that HSV-1 C7 in complementation group 1–3 also induces a thermolabile DNA polymerase.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-54-1-219
1981-05-01
2022-01-23
Loading full text...

Full text loading...

/deliver/fulltext/jgv/54/1/JV0540010219.html?itemId=/content/journal/jgv/10.1099/0022-1317-54-1-219&mimeType=html&fmt=ahah

References

  1. Allen G. P., O’callaghan D. J., Randall C. C. 1977; Purification and characterisation of equine herpesvirus-induced DNA polymerase. Virology 76:395–408
    [Google Scholar]
  2. Aron G. M., Purifoy D. J. M., Schaffer P. A. 1975; DNA synthesis and DNA polymerase activity of herpes simplex virus type 1 temperature-sensitive mutants. Journal of Virology 16:498–507
    [Google Scholar]
  3. Chartrand P., Stow N. D., Timbury M. C., Wilkie N. M. 1979; Physical mapping of PAA mutations of herpes simplex virus type 1 and type 2 by intertypic marker rescue. Journal of Virology 31:265–276
    [Google Scholar]
  4. Chartrand P., Crumpacker C. S., Schaffer P. A., Wilkie N. M. 1980; Physical and genetic analysis of the herpes simplex virus DNA polymerase locus. Virology 103:311–326
    [Google Scholar]
  5. Crumpacker C. S., Chartrand P., Subak-Sharpe J. H., Wilkie N. M. 1980; Resistance of herpes simplex virus to acycloguanosine-genetic and physical analysis. Virology 105:171–184
    [Google Scholar]
  6. Honess R. W., Roizman B. R. 1974; Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins. Journal of Virology 14:8–19
    [Google Scholar]
  7. Honess R. W., Watson D. H. 1977; Herpes simplex virus resistance and sensitivity to phosphonoacetic acid. Journal of Virology 21:584–600
    [Google Scholar]
  8. Knopf K. W. 1979; Properties of herpes simplex virus DNA polymerase and characterization of its associated exonuclease activity. European Journal of Biochemistry 98:231–244
    [Google Scholar]
  9. Ostrander M., Cheng Y. C. 1980; Properties of herpes simplex type 1 and type 2 DNA polymerase. Biochimica et Biophysica Acta 609:232–245
    [Google Scholar]
  10. Parris D. S., Courtney R. J., Schaffer P. A. 1978; Temperature-sensitive mutants of herpes simplex virus type 1 defective in transcriptional and post-transcriptional functions required for viral DNA synthesis. Virology 90:177–186
    [Google Scholar]
  11. Powell K. L., Purifoy D. J. M. 1977; Nonstructural proteins of herpes simplex virus. I. Purification of the induced DNA polymerase. Journal of Virology 24:618–626
    [Google Scholar]
  12. Purifoy D. J. M., Powell K. L. 1977; Herpes simplex virus DNA polymerase as the site of phosphonoacetate sensitivity: temperature-sensitive mutants. Journal of Virology 24:470–477
    [Google Scholar]
  13. Purifoy D. J. M., Lewis R. B., Powell K. L. 1977; Identification of the herpes simplex virus DNA polymerase gene. Nature, London 269:621–623
    [Google Scholar]
  14. Schaffer P. A., Aron G. M., Biswal N., Benyesh-Melnick M. 1973; Temperature-sensitive mutants of herpes simplex virus type 1: isolation, complementation and partial characterization. Virology 52:57–71
    [Google Scholar]
  15. Schaffer P. A., Carter V. C., Timbury M. C. 1978; Collaborative study of temperature-sensitive mutants of herpes simplex virus types 1 and 2. Journal of Virology 27:490–504
    [Google Scholar]
  16. Weissbach A., Hong S. C. L., Aucker J., Muller R. 1973; Characterization of herpes simplex virus induced deoxyribonucleic acid polymerase. Journal of Biological Chemistry 248:6270–6277
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-54-1-219
Loading
/content/journal/jgv/10.1099/0022-1317-54-1-219
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error