1887

Abstract

Summary

Four structural polypeptides of Hazara virus, an agent closely related to the Crimean—Congo haemorrhagic fever (C-CHF) viruses, were resolved by SDS—polyacrylamide gel electrophoresis. Three glycoproteins were identified (mol. wt. 84000, 45000 and 30000) and were found to be associated with the virion envelope. A fourth polypeptide (mol. wt. 52000) was non-glycosylated and associated with the nucleocapsid. The structural proteins of Hazara virus differ markedly from those reported for other bunyaviruses.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-53-1-169
1981-03-01
2024-04-25
Loading full text...

Full text loading...

/deliver/fulltext/jgv/53/1/JV0530010169.html?itemId=/content/journal/jgv/10.1099/0022-1317-53-1-169&mimeType=html&fmt=ahah

References

  1. Begum F., Wisseman C. L. Jr, Traub R. 1970a; Tick-borne viruses of West Pakistan. I. Isolation and general characteristics. American Journal of Epidemiology 92:180–191
    [Google Scholar]
  2. Begum F., Wisseman C. L. Jr, Casals J. 1970b; Tick-borne viruses of West Pakistan. II. Hazara virus, a new agent isolated from Ixodes redikorzevi ticks from the Kaghan Valley, W. Pakistan. American Journal of Epidemiology 92:192–194
    [Google Scholar]
  3. Bishop D. H. L., Calizhen C. H., Casals J., Chumakov M. P., Gaidamovich S. Y. A., Hannoun C., Lvov D. K., Marshall I., Oker-Blom N., Petterson R., Porterfield J. S., Russell P. K., Shope R. E., Westway R. G. 1980; Bunyaviridae. Intervirology (in press)
    [Google Scholar]
  4. Casals J., Tignor G. H. 1974; Neutralization and haemagglutination - inhibition tests with Crimean haemorrhagic fever-Congo virus. Proceedings of the Society for Experimental Biology and Medicine 145:960–966
    [Google Scholar]
  5. Casals J., Tignor G. H. 1980; The Nairovirus genus: serological relationships. Intervirology (in press)
    [Google Scholar]
  6. Hubbard A. L., Cohn Z. A. 1972; The enzymatic iodination of the red cell membrane. Journal of Cell Biology 55:390–405
    [Google Scholar]
  7. Jelinkova A., Benda R., Novak M. 1975; Electron microscope demonstration of Crimean hemorrhagic fever virus in CV-1 cells. Acta Virologica 19:369–373
    [Google Scholar]
  8. Korolev M. B., Donets M. A., Rubin S. G., Chumakov M. P. 1976; Morphology and morphogenesis of Crimean hemorrhagic fever virus. Archives of Virology 50:169–172
    [Google Scholar]
  9. Laemmli U. K. 1970; Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, London 227:680–685
    [Google Scholar]
  10. Murphy F. A., Harrison A. K., Whitfield S. G. 1973; Bunyaviridae: morphologic and morphogenetic similarities of Bunyamwera serologic supergroup viruses and several other arthropod-borne viruses. Inlervirology 1:297–316
    [Google Scholar]
  11. Naito S., Matsumoto S. 1979; Identification of cellular actin within the rabies virus. Virology 91:151–163
    [Google Scholar]
  12. Obijeski J. F., Murphy F. A. 1977; Bunyaviridae: recent biochemical developments. Journal of General Virology 37:1–14
    [Google Scholar]
  13. Pedersen C. E. Jr, Eddy G. A. 1975; Comparative analyses of members of the Venezuelan equine encephalomyelitis virus complex. American Journal of Epidemiology 101:245–252
    [Google Scholar]
  14. Porterfield J. S., Casals J., Chumakov M. P., Gaidamovich S. Y. A., Hannoun C., Holmes I. H., Horzinek M. C., Mussgay M., Oker-Blom N., Russell P. K. 1975/76; Bunyaviruses and Bunyaviridae. Intervirology 6:13–24
    [Google Scholar]
  15. Rosato R. R., Robbins M. L., Eddy G. A. 1974; Structural components of Oriboca virus. Journal of Virology 13:780–787
    [Google Scholar]
  16. Smirnova S. B., Shestopalova N. M., Reingold V. N., Zubri G. L., Chumakov M. P. 1977; Experimental Hazara virus infection in mice. Acta Virologica 21:128–132
    [Google Scholar]
  17. Weber K., Osborn M. 1969; The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. Journal of Biological Chemistry 244:4406–4412
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-53-1-169
Loading
/content/journal/jgv/10.1099/0022-1317-53-1-169
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error