1887

Abstract

Summary

The pp60 kinase activity of cells infected with temperature-conditional mutants of Rous sarcoma virus (RSV), which induce only a partial transformation, was compared to the pattern of transformation parameters induced by these mutants. The GI251-infected cells were thermosensitive for hexose transport, fibrinolysis, morphological alterations and pp60 kinase activity, but cold-sensitive for loss of growth control. The GI253-infected cells were similar to GI251-infected cells except that they were only slightly cold-sensitive for loss of growth control and had a very low pp60 kinase activity which was temperature-insensitive. Thus, the pp60 kinase activity measured with IgG as a substrate did not correlate in a consistent way with any of the measured parameters of transformation.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-52-2-395
1981-02-01
2019-11-19
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-52-2-395
Loading

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error