The major capsid protein of bovine papilloma virus type 1 (BPV-1) was isolated by gel filtration following disruption of purified virus particles with guanidine hydrochloride. The capsid protein, VP1, has a mol. wt. of about 53500. Amino acid composition studies of VP1 showed that it is a highly acidic protein containing almost twice the average number of acidic residues than basic residues. Relatedness was observed between VP1 and the major capsid proteins of simian virus 40 (SV40) and polyoma virus.
DayhoffM. O.,
HuntL. T.,
Hurst-CalderoneS.1978; Composition of proteins. In Atlas of Protein Sequences and Structure pp 361–365 Edited by
DayhoffM. O.
Maryland: The National Biomedical Research Foundation;
FavreM.,
BreitburdF.,
CroissantO.,
OrthG.1977; Chromatin-like structure obtained after alkaline disruption of bovine and human papilloma viruses. Journal of Virology 21:1205–1209
HugliT. E.,
MooreS. J.1972; Determination of the tryptophan content of proteins by ion exchange chromatography of alkaline hydrolysates. Journal of Biological Chemistry 247:2828–2834
ItoY.1962; Relationship of components of papilloma virus to papilloma and carcinoma cells. Cold Spring Harbor Symposia on Quantitative Biology 27:387–394
JablonskaS.,
DabrowskiJ.,
JakubowiczK.1972; Epidermodysplasia verruciformis as a model: studies on the role of papovaviruses in oncogenesis. Cancer Research 32:583–589
JarrettW. F. H.,
MurphyJ.,
O’neilB. L.,
LairdH. M.1978; Virus-induced papillomas of the alimentary tract of cattle. International Journal of Cancer 22:323–328
KiddJ. C.,
RousP.1940; A transplantable rabbit carcinoma originating in a virus-induced papilloma and containing the virus in a masked or altered form. Journal of Experimental Medicine 71:813–838
LakeR. S.,
BarbanS.,
SalzmanN.1973; Resolution and identification of the core deoxynucleoproteins of the simian virus 40. Biochemical and Biophysical Research Communications 54:640–647
LancasterW. D.,
OlsonC.,
MeinkeW.1977; Bovine papilloma virus: presence of virus-specific DNA sequences in naturally occurring equine tumors. Proceedings of the National Academy of Sciences of the United States of America 74:524–528
MurakamiW. T.,
FineR.,
HarringtonM. R.,
Ben-SassanZ.1968; Properties and amino acid composition of polyoma virus purified by zonal ultracentrifugation. Journal of Molecular Biology 36:153–166
OlsonC.,
CookR. H.1951; Cutaneous sarcoma-like lesions of the horse caused by the agent of bovine papilloma. Proceedings of the Society for Experimental Biology and Medicine 77:281–284
OrthG.,
BrietburdF.,
FavreM.,
CroissantO.1977; Papilloma viruses: possible role in human cancer. In Origins of Human Cancer pp 1048–1068 Edited by
WatsonJ.
New York: Cold Spring Harbor Laboratory;
PfisterH.,
LinzU.,
GissmanL.,
HuchthausenB.,
HoffmannD.,
Zur HausenH.1979; Partial characterization of a new type of bovine papilloma virus. Virology 96:1–8
ShahK. V.,
DanielR. W.,
KelleyT. J.Jr1977a; Immunological relatedness of papovaviruses of the simian virus 40-polyoma subgroups. Infection and Immunity 18:558–560
ShahK. V.,
OzerH. L.,
GhageyH. N.,
KelleyT. J.Jr1977b; Common structural antigen of papovaviruses of the simian virus 40-polyoma subgroup. Journal of Virology 21:179–186
YabeY.,
SadakaneH.1975; The virus of epidermodysplasia verruciformis: electron microscope and fluorescent antibody studies. Journal of Investigative Dermatology 65:324–330