1887

Abstract

SUMMARY

The physical mapping of six mutations of herpes simplex virus type 2 (HSV-2) is presented. The results were obtained from 14 separate intratypic marker rescue experiments and the analysis of 20 HSV-1/HSV-2 intertypic recombinants. The order of these mutations on the physical map of HSV-2 is unambiguous and correlates almost exactly with the previously published genetic map of Timbury & Calder (1976). One of the mutants studied (HSV-2 12) has apparently two distinct conditionally lethal mutations, one in the long and the other in the short region of the HSV genome.

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1981-01-01
2022-01-20
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