1887

Abstract

SUMMARY

Two virus-induced polypeptides are preferentially released into the culture medium of owl monkey kidney cells productively infected with herpesvirus saimiri (HVS). These polypeptides have apparent mol. wt. of 160 × 10 and 28 × 10 and are the major virus-induced polypeptides in a membrane fraction from infected cells. Both these excreted polypeptides co-migrate with virus structural proteins and are selectively released from enveloped virus particles by treatment with Nonidet-P40.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-51-2-445
1980-12-01
2022-01-18
Loading full text...

Full text loading...

/deliver/fulltext/jgv/51/2/JV0510020445.html?itemId=/content/journal/jgv/10.1099/0022-1317-51-2-445&mimeType=html&fmt=ahah

References

  1. Ben-Porat T., Kaplan A. S. 1970; Synthesis of proteins in cells infected with herpesvirus. V. Viral glycoproteins. Virology 41:265–273
    [Google Scholar]
  2. Deinhardt F., Falk L., Wolfe L. G. 1973; Simian herpesviruses. Cancer Research 33:1424–1426
    [Google Scholar]
  3. Falk L. A., Wolfe L. G., Deinhardt F. 1972; Isolation of Herpesvirus saimiri from blood of squirrel monkeys (Saimiri sciureus). Journal of the National Cancer Institute 48:1499–1505
    [Google Scholar]
  4. Falk L. A., Wright J., Deinhardt F., Wolfe L., Schaffer P., Benyesh-Melnick M. 1976; Experimental infection of squirrel and marmoset monkeys with attenuated Herpesvirus saimiri. Cancer Research 36:707–710
    [Google Scholar]
  5. Fleckenstein B. 1979; Oncogenic herpesviruses of non-human primates. Biochimica et Biophysica Acta 560:301–342
    [Google Scholar]
  6. Gibson W., Roizman B. 1972; Proteins specified by herpes simplex virus. Ⅲ. Characterisation and composition of multiple capsid forms of subtypes 1 and 2. Journal of Virology 10:1044–1052
    [Google Scholar]
  7. Heine J. W., Honess R. W., Cassai E., Roizman B. 1974; Proteins specified by herpes simplex virus. Ⅻ. The virion polypeptides of type 1 strains. Journal of Virology 14:640–651
    [Google Scholar]
  8. Kaplan A. S., Erickson J. S. R., Ben-Porat T. 1975; Synthesis of proteins in cells infected with herpesvirus. X. Proteins excreted by cells infected with herpes simplex virus, types 1 and 2. Virology 64:132–143
    [Google Scholar]
  9. Laufs R. 1974; Immunization of marmoset monkeys with a killed oncogenic herpesvirus. Nature, London 249:571–572
    [Google Scholar]
  10. Laufs R., Steinke H. 1975; Vaccination of non-human primates against malignant lymphoma. Nature, London 253:71–72
    [Google Scholar]
  11. Norrild B., Vestergaard B. F. 1979; lmmunoelectrophoretic identification and purification of herpes simplex virus antigens released from infected cells in tissue culture. Intervirology 11:104–110
    [Google Scholar]
  12. Randall R. E., Killington R. A., Watson D. H. 1980; Glycoproteins with type common and type specific antigenic sites excreted from cells infected with herpes simplex virus types I and 2. Journal of General Virology 48:297–310
    [Google Scholar]
  13. Sarmiento M., Spear P. G. 1979; Membrane proteins specified by herpes simplex viruses. IV. Conformation of virion glycoprotein designated VP 7 (B2). Journal of Virology 29:1159–1167
    [Google Scholar]
  14. Schaffer P. A., Falk L. A., Deinhardt F. 1975; Attenuation of Herpesvirus saimiri for marmosets after successive passage in cell culture at 39 °C. Journal of the National Cancer Institute 55:1243–1246
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-51-2-445
Loading
/content/journal/jgv/10.1099/0022-1317-51-2-445
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error