1887

Abstract

SUMMARY

After multiplication in the continuous human cell lines HeLa, KB, and Hep 2, echovirus 11 (prototype strain Gregory) loses its haemagglutinating (HA) activity but retains infectivity. After seven passages in Hela cells the HA activity was not restored. There was no correlation between the loss of HA activity and modification of thermosensitivity, plaque morphology, surface properties and antigenicity. HA echovirus 11 particles did not show the properties of defective interfering (DI) particles as described for poliovirus.

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1980-11-01
2024-04-19
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References

  1. Böttiger M. 1968; Ret marker tests on isolates from WM3 and Sabin type 3 attenuated poliovirus vaccines. Archiv für die gasamte Virusforschung 25:299–307
    [Google Scholar]
  2. Burness A. T. H. 1969; Purification and separation of encephalomyocarditis virus variant by chromatography on calcium phosphate. In Fundamental Techniques in Virology pp 94–109 Edited by Habel K., Salzman N. P. New York and London: Academic Press;
    [Google Scholar]
  3. Cole C. N., Baltimore D. 1973a; Defective interfering particles of poliovirus. II. Nature of the defect. Journal of Molecular Biology 76:325–343
    [Google Scholar]
  4. Cole C. N., Baltimore D. 1973b; Defective interfering particles of poliovirus. III. Interference and enrichment. Journal of Molecular Biology 76:345–361
    [Google Scholar]
  5. Cole C. N., Baltimore D. 1973c; Defective interfering particles of poliovirus. IV. Mechanisms of enrichment. Journal of Virology 11:1414–1426
    [Google Scholar]
  6. Cole C. N., Smoler D., Wimmer E., Baltimore D. 1971; Defective interfering particles of poliovirus. Isolation and physical properties. Journal of Virology 7:478–485
    [Google Scholar]
  7. Cova L., Aymard M. 1978; Studies on the loss of haemagglutinating properties of echoviruses. IVth International Congress for Virology. The Hague pp 645 (abstract)
    [Google Scholar]
  8. Halperen S., Stone H.O., Korant B.D. 1973; Isolation of glucosamine from the capsids of a picornavirus. Journal of General Virology 20:267–276
    [Google Scholar]
  9. Huang A. S., Baltimore D. 1977; Defective interfering animal viruses. In Comprehensive Virology pp 73–116 Edited by Fraenkel-Conrat H., Wagner R. R. New York: Plenum Press;
    [Google Scholar]
  10. Maisel J., Moscovici C., La placa M. 1961; Susceptibility of human tumor cells to echoviruses and loss of haemagglutinating capacity of some of the adapted viruses. Archiv für die gesamte Virusforschung 11:209–214
    [Google Scholar]
  11. Moscovici C., La placa M. 1961; Further studies on the loss of the haemagglutinating capacity of Echo-virus type 19 after adaptation in Hela cells. Giornale de Microbiologia 9:135–141
    [Google Scholar]
  12. Podoplekin V. D. 1964; Effect of tissue cultures on the haemagglutinating properties of echoviruses and mechanism of the interaction of these viruses with erythrocytes. Acta Virologica 8:254–262
    [Google Scholar]
  13. Schmidt N. J., Dennis J., Hoffman M. N., Lennette E. H. 1964; Inhibitors of echovirus and reovirus haemagglutination. Journal of Immunology 93:367–377
    [Google Scholar]
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