1887

Abstract

SUMMARY

mutants in from the Prague and Schmidt-Ruppin strains of Rous sarcoma virus (RSV) were used to superinfect chicken and quail cells chronically infected with the Bryan strain of RSV. No wild-type recombinants and few double-defective virions were produced. These results indicate that genetic recombination does not occur with high frequency in these heterologous crosses even if all infectious virus is derived from doubly infected cells.

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1980-09-01
2022-01-22
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References

  1. Balduzzi P. C. 1976; Cooperative transformation studies with temperature sensitive mutants of Rous sarcoma virus. Journal of Virology 18:332–343
    [Google Scholar]
  2. Balduzzi P. C., Beamand J. A., Christensen J. R., Pearson Y. M., Wyke J. A. 1978; Provisional mapping of transformation defective temperature sensitive mutants of Rous sarcoma virus. In Avian RNA Tumor Viruses pp 112–121 Edited by Barlati S., DeGiuli-Morghen C. Padua: Piccin Medical Books;
    [Google Scholar]
  3. Hunter E. 1978; The mechanism for genetic recombination in the avian retroviruses. Current Topics in Microbiology and Immunology 79:295–309
    [Google Scholar]
  4. Kawai S., Hanafusa H. 1976; Recombination between a temperature-sensitive mutant and a deletion mutant of Rous sarcoma virus. Journal of Virology 19:389–397
    [Google Scholar]
  5. Martin O. S. 1970; Rous sarcoma virus: a function required for maintenance of the transformed state. Nature, London 227:1021–1023
    [Google Scholar]
  6. Murphy H. M. 1977; A new replication-defective variant of the Bryan high titre strain of Rous sarcoma virus. Virology 77:705–721
    [Google Scholar]
  7. Reed L. J., Muench H. 1938; A simple method of estimating fifty percent end points. American Journal of Hygiene 27:493–497
    [Google Scholar]
  8. Weiss R. A., Mason W. S., Vogt P. K. 1973; Genetic recombinants and heterozygotes derived from endogenous and exogenous avian RNA tumor viruses. Virology 52:535–552
    [Google Scholar]
  9. Wyke J. A. 1973a; The selective isolation of temperature-sensitive mutants of Rous sarcoma virus. Virology 52:587–590
    [Google Scholar]
  10. Wyke J. A. 1973b; Complementation of transforming functions by temperature sensitive mutants of Rous sarcoma virus. Virology 54:28–36
    [Google Scholar]
  11. Wyke J. A., Bell J. G., Bemand J. A. 1974; Genetic recombination among temperature sensitive mutants of Rous sarcoma virus. Cold Spring Harbor Symposia on Quantitative Biology 39:897–905
    [Google Scholar]
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