Sensitivity of Viruses to Phosphorylated 9-(2-hydroxyethoxymethyl)Guanine Revealed in TK-transformed Cells

References

1. Elion G. B., Furman P. A., Fyee J. A., De Miranda P., Beauchchamp L., Schaeffar H. J. 1977; Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine. Proceedings of the National Academy of Sciences of the United States of America 74:5716–5720
   [Google Scholar]
2. Field H. J., Bell S. E., Elion O. B., Nash A. A., Wildy P. 1979; Effect of acycloguanosine treatment of acute and latent herpes simplex infections in mice. Antimicrobial Agents and Chemotherapy 15:554–561
   [Google Scholar]
3. Field H. J., Darby G., Wildy P. 1980; Isolation and characterization of acyclovir-resistant mutants of herpes simplex virus. Journal of General Virology 49: (this part)
   [Google Scholar]
4. Fyfe J. A., Keller P. M., Furman P. A., Miller R. L., Elion G. B. 1978; Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound, 9-(2-hydroxyethoxymethyl) guanine. Journal of Biological Chemistry 253:8721–8727
   [Google Scholar]
5. Klein R. J., Friedman-Kien A. E., De Stefano E. 1979; Latent herpes simplex virus infection in sensory ganglia of hairless mice prevented by acycloguanosine. Antimicrobial Agents and Chemotherapy 15:723–729
   [Google Scholar]
6. Minson A. C., Wildy P., Buchan A., Darby G. 1978; Introduction of the herpes simplex virus thymidine kinase gene into mouse cells using virus DNA or transformed cell DNA. Cell 13:581–587
   [Google Scholar]
7. Munyon W., Kraiselburp E., Davis S., Mann J. 1971; Transfer of thymidine kinase to thymidine kinaseless L-cells by infection with ultraviolet irradiated herpes simplex virus. Journal of Virology 7:813–820
   [Google Scholar]
8. Nishiyama Y., Rapp F. 1979; Anticellular effects of 9-(2-hydroxyethoxymethyl)guanine against herpes simplex virus transformed cells. Journal of General Virology 45:227–230
   [Google Scholar]
9. Park N. H., Pavan-Langston D., McLean S. L., Albert D. M. 1979; Therapy of experimental herpes simplex encephalitis with aciclovir in mice. Antimicrobial Agents and Chemotherapy 15:775–779
   [Google Scholar]
10. Pavan-Langston N. H. D., Lass J. H. 1979; Herpetic ganglionic latency, aciclovir and vidarabine therapy. Archives of Ophthalmology 97:1508–1510
    [Google Scholar]
11. Schaeffer H. J., Beauchamp L., De Miranda P., Elion G. B., Bauer D. J., Collins P. 1978; 9-(2-hydroxy-ethoxymethyl)guanine activity against viruses of the herpes group. Nature, London 272:583–585
    [Google Scholar]
12. Wigler M., Silverstein S., Lee L.S., Pellicer A., Cheng Y.C., Axel R. 1977; Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells. Cell 11:223–232
    [Google Scholar]