1887

Abstract

SUMMARY

Acyclovir (ACV) was effective in preventing recurrence of herpes simplex in mice whose skin was stripped with cellophane tape. Treatment with ACV did not eliminate latent herpes simplex virus from the cervical ganglia.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-48-2-417
1980-06-01
2024-04-19
Loading full text...

Full text loading...

/deliver/fulltext/jgv/48/2/JV0480020417.html?itemId=/content/journal/jgv/10.1099/0022-1317-48-2-417&mimeType=html&fmt=ahah

References

  1. Crumpacker C. S., Schnipper L. E., Zma J. A., Levin M. J. 1979; Growth inhibition by acycloguanosine of herpesviruses isolated from human infections. Antimicrobial Agents and Chemotherapy 15:642–645
    [Google Scholar]
  2. Elion O. B., Furman P. A., Fyee J. A., De Miranda P., Beauchamp L., Schaeffar H. J. 1977; Selective action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine. Proceedings of the National Academy of Sciences of the United States of America 74:5716–5720
    [Google Scholar]
  3. Field H. J., Bell S. E., Elion O. B., Nash A. A., Wildy P. 1979; Effect of acycloguanosine treatment on acute and latent herpes simplex infections in mice. Antimicrobial Agents and Chemotherapy 15:554–561
    [Google Scholar]
  4. Hill T. J., Field H. J., Blyth W. A. 1975; Acute and recurrent infection with herpes simplex virus in the mouse: a model for studying latency and recurrent disease. Journal of General Virology 28:341–353
    [Google Scholar]
  5. Hill T. J., Blyth W. A., Harbour D. A. 1978; Trauma to the skin causes recurrence of herpes simplex in the mouse. Journal of General Virology 39:21–28
    [Google Scholar]
  6. Klein R. J., Friedman-Kien A. E., De Stefano E. 1979; Latent herpes simplex virus infection in sensory ganglia of hairless mice prevented by acycloguanosine. Antimicrobial Agents and Chemotherapy 15:723–729
    [Google Scholar]
  7. Pavan-Langston D., Park N. H., Lass J. H. 1979; Herpetic ganglionic latency. Acyclovir and vidarabine therapy. Archives of Ophthalmology 97:1508–1510
    [Google Scholar]
  8. Schaefarr H. J., Beauchamp L., De Miranda P., Elion G. B., Bauer D. J., Collins P. 1978; 9-(2- hydroxy- ethoxymethyl) guanine activity against viruses of the herpes group. Nature, London 272:583–585
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-48-2-417
Loading
/content/journal/jgv/10.1099/0022-1317-48-2-417
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error