1887

Abstract

SUMMARY

A focus-forming assay for the quantification of defective interfering (DI) particles of vesicular stomatitis virus (VSV) is described. This assay is based on the procedure described for lymphocytic choriomeningitis (LCM) virus by Popescu ., (1976). Under appropriate conditions this focus-forming assay can quantify fewer than 100 DI particles/ml in a preparation containing a large number of infectious particles.

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/content/journal/jgv/10.1099/0022-1317-48-1-237
1980-05-01
2021-10-25
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References

  1. Bellett A. J. D., Cooper P. D. 1959; Some properties of the transmissable interfering components of vesicular stomatitis virus preparations. Journal of General Virology 21:498–501
    [Google Scholar]
  2. Huang A. S. 1973; Defective interfering viruses. Annual Revenue of Microbiology 27:101–118
    [Google Scholar]
  3. Huang A. S., Baltimore D. 1970; Defective viral particles and virus disease processes. Nature, London 226:325–327
    [Google Scholar]
  4. Popescue M., Schaefer H., Lehman-Grube F. 1976; Homologous interference of lymphocytic choriomeningitis virus: detection and measurement of interference focus-forming units. Journal of Virology 20:1–8
    [Google Scholar]
  5. Thacore H. 1976; Rescue of vesicular stomatitis virus from homologous and heterologous interferon-induced resistance in human cell cultures by poxviruses. Infection and Immunity 14:311–314
    [Google Scholar]
  6. Winship T. R., Thacore H. R. 1979; Inhibition of vesicular stomatitis virus-defective interfering particle synthesis by Shope fibroma virus. Virology 93:515–526
    [Google Scholar]
  7. Youngner J. S., Scott A. W., Hallum J. V., Stinebring W. R. 1966; Interferon production by inactivated Newcastle disease virus in cell cultures and in mice. Journal of Bacteriology 92:862–868
    [Google Scholar]
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