1887

Abstract

SUMMARY

The biochemistry of vaccinia virus replication in two permissive (BSC-40, L-929), and two non-permissive (CHO, MDBK) cell lines has been compared. While CHO and MDBK cells differentially allowed expression of the various stages in the vaccinia developmental programme, neither cell supported production of any infectious progeny virions.

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1980-04-01
2024-11-07
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References

  1. Drillien R., Spehner D., Kirn A. 1978; Host range restriction of vaccinia virus in Chinese hamster ovary cells: relationship to shut-off of protein synthesis. Journal of Virology 28:843–850
    [Google Scholar]
  2. Hruby D. E., Guarino L. A., Kates J. R. 1979a; Vaccinia virus replication. I. Requirement for the host-cell nucleus. Journal of Virology 29:705–715
    [Google Scholar]
  3. Hruby D. E., Lynn D. L., Kates J. R. 1979b; Vaccinia virus replication requires active participation of the host cell transcriptional apparatus. Proceedings of the National Academy of Sciences of the United States of America 76:1887–1890
    [Google Scholar]
  4. Joklik W. K., Becker Y. 1964; The replication and uncoating of vaccinia DNA. Journal of Molecular Biology 10:452–474
    [Google Scholar]
  5. Moss B. 1974; Reproduction of poxviruses. In Comprehensive Virology vol 3 pp 405–474 Edited by FraenkelConrat H., Wagner R. R. New York: Plenum Press;
    [Google Scholar]
  6. Moss B., Rosenblum E. N., Katz E., Grimley P. M. 1969; Rifampicin: a specific inhibitor of vaccinia virus assembly. Nature, London 224:1280–1284
    [Google Scholar]
  7. Pennington T. H. 1974; Vaccinia virus polypeptide synthesis: sequential appearance and stability of pre- and post-replicative polypeptides. Journal of General Virology 25:433–444
    [Google Scholar]
  8. Studier F. W. 1973; Analysis of bacteriophage T7 early RNAs and proteins on slab gels. Journal of Molecular Biology 79:237–248
    [Google Scholar]
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