1887

Abstract

SUMMARY

The synthesis of polypeptides in infected Vero cells has been studied with two tissue culture adapted strains of mumps virus. Minor differences between the strains are found in the mobilities of the virus-specific polypeptides in SDS-PAGE. Eight virus-induced polypeptides have been identified with mol. wt. of 180K, 80K, 71K, 69K, 45K, 39K, 23K and 17K. These may correspond to the L, HN, N, F, P, M, C and S polypeptides identified in other paramyxoviruses. The 69K F glycoprotein is probably a precursor for glycopolypeptides F and F with mol. wt. 61K and 14K, respectively.

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1980-02-01
2024-04-23
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References

  1. Buetti E., Choppin P. W. 1977; The transcriptase complex of the paramyxovirus SV5. Virology 82:493–508
    [Google Scholar]
  2. Huppertz H. I., Hall W. W., Ter meulen V. 1977; Polypeptide composition of mumps virus. Medical Microbiology and Immunology 163:251–259
    [Google Scholar]
  3. Jensik S. C., Silver S. 1976; Polypeptides of mumps virus. Journal of Virology 17:363–373
    [Google Scholar]
  4. Kingsbury D. W., Bratt M. A., Choppin P. W., Hansen R. P., Hosaka Y., Ter Meulen V., Norrby E., Plowright W., Rott R., Wunner W. H. 1978; Paramyxoviridae. Intervirology io:137–152
    [Google Scholar]
  5. Klenk H.-D., Rott R., Nagai Y., Berk W. 1978; The pathogenicity of Newcastle disease virus as depending on the structure of the viral glycoproteins. In Negative Strand Viruses and the Host Cell pp 607–616 Edited by Mahy B. W. J., Barry R. D. London: Academic Press;
    [Google Scholar]
  6. Lamb R. A., Choppin P. W. 1978; Determination by peptide mapping of the unique polypeptides in Sendai virions and infected cells. Virology 84:469–478
    [Google Scholar]
  7. Mountcastle W. E., Choppin P. W. 1977; A comparison of the polypeptides of four measles virus strains. Virology 78:463–474
    [Google Scholar]
  8. Örvell C. 1978a; Immunological properties of purified mumps virus glycoproteins. Journal of General Virology 41:517–526
    [Google Scholar]
  9. Örvell C. 1978b; Structural polypeptides of mumps virus. Journal of General Virology 41:527–539
    [Google Scholar]
  10. Rima B. K., Martin S. J. 1979; Effect of undiluted passage on the polypeptides of measles virus. Journal of General Virology 44:135–144
    [Google Scholar]
  11. Scheid A., Graves M. C., Silver S. M., Choppin P. W. 1978; Studies on the structure and functions of paramyxovirus glycoproteins. In Negative Strand Viruses and the Host Cell pp 181–193 Edited by Mahy B. W. J., Barry R. D. London: Academic Press;
    [Google Scholar]
  12. Tyrrell D. L. J., Norrby E. 1978; Structural polypeptides of measles virus. Journal of General Virology 39219–229
    [Google Scholar]
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