1887

Abstract

SUMMARY

When an avian sarcoma virus (ASV), subgroup C Bratislava 77 (B77-C) was inoculated into duck embryo fibroblast cultures (DEF) at a m.o.i. of 0.02, its replication was retarded by about 3 days compared with that in chick embryo fibroblast cultures (CEF). A transformation-defective () mutant was isolated during this period of retardation. Unlike the sarcoma virus, this mutant replicated in both DEF and CEF with no retardation, even at a low m.o.i. The subgroup C Prague strain of Rous sarcoma virus (PR-C), which can infect DEF, also replicated in DEF slower than its mutant, PR-C, at a m.o.i. of 0.02.

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/content/journal/jgv/10.1099/0022-1317-45-1-99
1979-10-01
2021-10-17
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