1887

Abstract

Summary

Monolayers of primary rabbit kidney cells infected with HSV type 1 bound lymphoblastoid (Raji) cells, to which the third component (C3) of the complement system had been attached (Raji-C3). This induction of cell contact did not occur on non-infected monolayers and was dependent on C3. The interaction could be suppressed by the presence of protease inhibitors (1 m-TLCK or-PMSF). The results are interpreted as indicating expression of protease activity on the surface of HSV-infected cells. This protease is characterized by its potential to activate C3 and its inhibition by TLCK.

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/content/journal/jgv/10.1099/0022-1317-45-1-241
1979-10-01
2019-11-14
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-45-1-241
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