1887

Abstract

SUMMARY

Polyadenylated transcripts synthesized by detergent-disrupted influenza virus resemble virus mRNAs in that they possess the complement of the 3′ terminus of the genome RNAs but lack sequences corresponding to the same 5′ terminal region, including the homologous sequence of nucleotides 1 to 22. Transcription is initiated at the 3′ terminus by both ApG and GpG as well as in the absence of added primer.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-44-3-599
1979-09-01
2024-12-05
Loading full text...

Full text loading...

/deliver/fulltext/jgv/44/3/JV0440030599.html?itemId=/content/journal/jgv/10.1099/0022-1317-44-3-599&mimeType=html&fmt=ahah

References

  1. Bosch F. X., Hay A. J., Skehel J. J. 1978; RNA and protein synthesis in a permissive and abortive influenza virus infection. In Negative Strand Viruses and the Host Cell pp 465–474 Edited by Barry R. D., Mahy B. W. J. New York: Academic Press;
    [Google Scholar]
  2. Bouloy M., Plotch S. J., Krug R. M. 1978; Globin mRNAs are primers for the transcription of influenza viral RNA in vitro. Proceedings of the National Academy of Sciences of the United States of America 75:4886–4890
    [Google Scholar]
  3. De Wachter R., Fiers W. 1967; Studies on the Bacteriophage MS2. IV. The 3 -OH terminal undercanucleotide sequence of the viral RNA chain. Journal of Molecular Biology 30:507–527
    [Google Scholar]
  4. Hay A. J. 1974; Studies on the formation of the influenza virus envelope. Virology 60:398–418
    [Google Scholar]
  5. Hay A. J., Lomniczi B., Bellamy A. R., Skehel J. J. 1977; Transcription of the influenza virus genome. Virology 83:337–355
    [Google Scholar]
  6. Hay A. J., Skehel J. J., Abraham G., Smith J. C., Fellner P. 1978; Structurally and functionally distinct influenza virus complementary RNAs. In Negative Strand Viruses and the Host Cell pp 313–323 Edited by Barry R. D., Mahy B. W. J. New York: Academic Press;
    [Google Scholar]
  7. Horisberger M. A. 1976; The ‘in vitro’ stimulation of the influenza transcriptase by ribosomes. FEBS Letters 63:134–136
    [Google Scholar]
  8. Krug R. M., Morgan M. A., Shatkin A. J. 1976; Influenza viral mRNA contains internal N6-methyl adenosine and 5′-terminal 7-methyl-guanosine in cap structures. Journal of Virology 20:45–53
    [Google Scholar]
  9. Mcgeoch D., Kitron N. 1975; Influenza virion RNA-dependent RNA polymerase: stimulation by guanosine and related compounds. Journal of Virology 15:686–695
    [Google Scholar]
  10. Plotch S., Krug R. M. 1977; Influenza virion transcriptase: the synthesis ‘in vitro‘ of large, poly A containing complementary RNA. Journal of Virology 21:24–34
    [Google Scholar]
  11. Plotch S. J., Krug R. M. 1978; Segments of influenza virus complementary RNA synthesized in vitro. Journal of Virology 25:579–586
    [Google Scholar]
  12. Plotch S. J., Tomasz J., Krug R. M. 1978; Absence of detectable capping and methylating enzymes in influenza virions. Journal of Virology 28:75–83
    [Google Scholar]
  13. Skehel J. J., Hay A. J. 1978; Nucleotide sequences at the 5′-termini of influenza virus RNAs and their transcripts. Nucleic Acids Research 5:1207–1219
    [Google Scholar]
  14. Skehel J. J., Hay A. J., Mccauley J., Florent G. 1978; Hybridization studies of influenza virus RNA transcripts. In Proceedings of the Symposium on Influenza and Hepatitis Moscow, 1978 (in the press)
    [Google Scholar]
/content/journal/jgv/10.1099/0022-1317-44-3-599
Loading
/content/journal/jgv/10.1099/0022-1317-44-3-599
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error