1887

Abstract

SUMMARY

Interferon production was inhibited in the Namalwa line of human lymphoblastoid cells by treatment with 2-deoxy--glucose or -glucosamine. -Glucosamine also inhibited protein synthesis and the cells were no longer viable, whereas 2-deoxy--glucose allowed protein and RNA synthesis to continue at control rates, and the cells remained fully viable. It is concluded that a glycosylation step is essential for production of lymphoblastoid interferon.

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1979-05-01
2021-10-20
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