RT Journal Article SR Electronic(1) A1 Wyke, John A. A1 Beamand, Jennifer A.YR 1979 T1 Genetic Recombination in Rous Sarcoma Virus: the Genesis of Recombinants and Lack of Evidence for Linkage between pol, env and src Genes in Three Factor Crosses JF Journal of General Virology, VO 43 IS 2 SP 349 OP 364 DO https://doi.org/10.1099/0022-1317-43-2-349 PB Microbiology Society, SN 1465-2099, AB SUMMARY Three factor crosses were performed between Rous sarcoma virus mutants with temperature-sensitive markers in the pol and src genes and host range markers in the env gene. A number of recombinant viruses appeared to segregate from virus particles which were heterozygous for all three genes under study. The frequency of various recombinant genotypes in the progeny was consistent with there being no greater linkage between the neighbouring gene pairs of pol and env and env and src than between the more distant pol and src. The significance of these results to proposed mechanisms of avian retrovirus recombination is discussed., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-43-2-349