1887

Abstract

SUMMARY

Virus-like particles were found in the E36 cells. One type, associated with centrioles, consisted of two concentric shells with a diam. of 50 to 60 nm. Some of these particles were seen budding through the plasma membrane giving rise to a free immature particle showing two concentric shells and an outer envelope. Concentration of the inner shell into a nucleoid results in a mature particle characterized by a nucleoid, mainly eccentrically located, surrounded by an intermediate layer and wrapped in an envelope. The diameter of the mature and immature particles was 75 to 85 nm. The morphogenesis of this virus-like particle resembles that of the oncoviruses.

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1978-11-01
2024-04-25
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References

  1. Bernhard W., Tournier P. 1964; Infection virale inapparente de céllules de hamsters décelée par la microscopie electronique. Annales de l’nstitut Pasteur Paris 107:447–452
    [Google Scholar]
  2. Calafat J., Ressang A. A. 1977; Morphogenesis of bovine leukemia virus. Virology 80:42–53
    [Google Scholar]
  3. Dalton A. J., Haguenau F. 1973; RNA tumor viruses. Introduction. In Ultrastructure of Animal Viruses. and Bacteriophages255–259 Dalton A. J., Haguenau E. New York and London: Academic Press, Inc;
    [Google Scholar]
  4. Dalton A. J., Heine U. I., Melnick J. L. 1975; Characterization of oncornaviruses and related viruses (A report.). Journal of the National Cancer Institute 55:941–943
    [Google Scholar]
  5. Epstein W. L., Fukuyama K., Benn M., Keston A. S., Brandt R. B. 1968; Transmission of a pigmented melanoma in Golden hamster by a cell-free ultrafiltrate. Nature, London 219:979–980
    [Google Scholar]
  6. Ford D. K., Yerganian G. 1958; Observations on the chromosomes of Chinese hamster cells in tissue culture. Journal of the National Cancer Institute 21:393–425
    [Google Scholar]
  7. Freeman A. E., Kelloff G. J., Vernon M. L., Lane W. T., Capps W. I., Bumgarner S. D., Turner H. C., Huebner R. J. 1974; Prevalence of endogenous type-c virus in normal hamster tissue and hamster tumors induced by chemical carcinogenesis, simian virus 40 and polyoma virus. Journal of the National Cancer Institute 52:1469–1476
    [Google Scholar]
  8. Gould R. R., Borisy G. G. 1977; The pericentriolar material in Chinese hamster ovary cells nucleates microtubule formation. The Journal of Cell Biology 73:601–615
    [Google Scholar]
  9. Kelloff G. J., Huebner R. J., Gilden R. V. 1973; Isolation and characterization of the hamster C-type viruses. In Unifying Concepts of Leukemia, Bibliotheca Haematologica 3961–68 Dutcher R. M., Chieco-Bianchi L. Basel: S. Karger;
    [Google Scholar]
  10. Stenback W. A., Van Hoosier G. L. Jun., Trentin J. J. 1966; Virus particles in hamster tumors revealed by electron microscopy. Proceedings of the Society for Experimental Biology and Medicine 122:1219–1223
    [Google Scholar]
  11. Takahashi M., Mishima Y. 1969; A sequence of virus-like particle formation in the ergatoplasm of Greene’s malignant melanoma cells. Cancer 24:904–911
    [Google Scholar]
  12. Wheatley D. N. 1974; Pericentriolar virus-like particles in Chinese hamster ovary cells. The Journal of General Virology 24:395–399
    [Google Scholar]
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