A type B phage P221, derived from recombination between a type A phage P22 and a type B phage , carries the protein coat of and the P22 early genes, at least the to 21 genes. One of the P221 strains, P221, is dismune over P221 lysogens and co-immune with P22. Thus it carries the gene (the second immunity region) of P22 to establish co-immunity with P22. Since the region and gene for somatic 0–1 antigen conversion of P22 are located between the and genes, the P221 prophage attachment site and 0–1 antigen of P221 lysogens were analysed. P221 prophage is integrated at the P22 site near the A region of the bacterial chromosomes and expresses the somatic 0–1 antigen.


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