%0 Journal Article %A Gangemi, J. David %A Rosato, Robert R. %A Connell, Edward V. %A Johnson, Edward M. %A Eddy, Gerald A. %T Structural Polypeptides of Machupo Virus %D 1978 %J Journal of General Virology, %V 41 %N 1 %P 183-188 %@ 1465-2099 %R https://doi.org/10.1099/0022-1317-41-1-183 %I Microbiology Society, %X SUMMARY The structural proteins of an arenavirus pathogen, Machupo virus, were compared to the structural proteins of two previously characterized non-pathogenic arenaviruses, Pichinde and Tacaribe, in SDS-polyacrylamide gels. Similarities in mol. wt. of the major structural proteins from both pathogenic and non-pathogenic viruses were apparent; however, some differences in the number of glycosylation properties of minor proteins were observed. Machupo virions contain two major protein species. The most prominent is a non-glycosylated protein with a mol. wt. of 68000, while the other was a glycosylated protein with a mol. wt. of 41000. Minor amounts of other proteins (mol. wt. 84000, 74000, 50000 and 15000) and a glycolipid were also observed. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-41-1-183