1887

Abstract

Summary

Rous sarcoma virus (RSV) mutants, which bear temperature sensitive () defects in both the maintenance of cell transformation and the expression of tumour specific cell surface antigen(s) (TSSA), have yielded a number of revertants. In seven revertants studied, the acquisition of wild type transforming capacities is always accompanied by a wild type TSSA expression. This strongly indicates that transformation and TSSA expression in RSV are affected by the same mutation.

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/content/journal/jgv/10.1099/0022-1317-40-3-701
1978-09-01
2024-04-24
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References

  1. Gelderblom H., Bauer H., Graf T. 1972; Cell surface antigens induced by avian RNA tumor viruses: detection by immunoferritin techniques. Virology 47:416–425
    [Google Scholar]
  2. Graf T., Friis R. R. 1973; Differential expression of transformation in rat and chicken cells infected with an avian sarcoma virus ts mutant. Virology 56:369–374
    [Google Scholar]
  3. Hayami M., Ignjatovic J., Bauer H. 1977; Avian retrovirus-induced surface antigens and their crossreactivity with chemically-transformed cells and primary embryonic cells of Japanese quails. International Journal of Cancer 20:729–737
    [Google Scholar]
  4. Hynes R. O., Wyke J. A. 1975; Alterations in surface proteins in chicken cells transformed by temperature-sensitive mutants of Rous sarcoma virus. Virology 64:492–504
    [Google Scholar]
  5. Kurth R. 1975; Differential induction of tumour antigens by transformation defective virus mutants. Journal of General Virology 28:167–177
    [Google Scholar]
  6. Kurth R. 1976; Surface alterations in cells infected by avian leukosis-sarcoma viruses. Biomembranes 8:167–233
    [Google Scholar]
  7. Kurth R., Bauer H. 1972; Cell surface antigens induced by RNA tumor viruses: detection by cytotoxic microassay. Virology 47:426–433
    [Google Scholar]
  8. Kurth R., Bauer H. 1973; Avian oncornavirus-induced tumor antigens of embryonic and unknown origin. Virology 56:496–504
    [Google Scholar]
  9. Kurth R., Bauer H. 1975; Avian RNA tumor viruses: a model for studying tumor associated cell surface alterations. Biochimica et Biophysica Acta Reviews on Cancer 417:1–23
    [Google Scholar]
  10. Kurth R., Friis R. R., Wyke J. A., Bauer H. 1975; Expression of tumor-specific surface antigens on cells infected with temperature-sensitive mutants of avian sarcoma virus. Virology 64:400–408
    [Google Scholar]
  11. Kurth R., Wyke J. A., Friis R. R., Rohrschneider L., Bauer H. 1976; The effect of transformation-defective avian oncornavirus mutants on tumor antigen expression. Journal of Supramolecular Structure 4:133–139
    [Google Scholar]
  12. Rohrschneider L. R., Bauer H., Bolognesi D. P. 1975; Group-specific antigenic determinants of the large envelope glycoprotein of avian oncornaviruses. Virology 67:234–241
    [Google Scholar]
  13. Toyoshima K., Vogt P. K. 1969; Temperature-sensitive mutants of an avian sarcoma virus. Virology 39:930–931
    [Google Scholar]
  14. Wainberg M. A., Phillips E. R. 1976; Immunity against avian sarcomas. Israel Journal of Medical Science 12:388–406
    [Google Scholar]
  15. Wyke J. A. 1973; The selective isolation of temperature-sensitive mutants of Rous sarcoma virus. Virology 52:587–590
    [Google Scholar]
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