1887

Abstract

SUMMARY

Calcium chloride (5 to 20 m) potentiated interferon production induced by rI:rC in L929 mouse fibroblasts up to a thousand-fold. Higher concentrations of calcium (20 to 65 m) mixed with rI:rC were associated with increased cytotoxicity and a more acidic medium, but were effective in enhancing interferon production if preparations were adjusted to a uniform pH. Although calcium increased cellular binding of H-rC:rI, only a partial correlation between binding and interferon production was observed.

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1978-08-01
2024-04-25
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