RT Journal Article SR Electronic(1) A1 Nishiyama, Yukihiro A1 Ito, Yasuhiko A1 Shimokata, KaoruYR 1978 T1 Properties of the Viruses Selected during Persistent Infection of L Cells with VSV JF Journal of General Virology, VO 40 IS 2 SP 481 OP 484 DO https://doi.org/10.1099/0022-1317-40-2-481 PB Microbiology Society, SN 1465-2099, AB SUMMARY Two virus clones, VSV-mp and VSV-sp, were isolated from L cells persistently infected with VSV (New Jersey serotype). Both clones were more temperature sensitive than the parent virus, VSV-o, and grew more slowly, gave smaller plaques, less c.p.e. and lower virus yields in L cells. Unlike the parent virus, both persistent viruses induced interferon production in L cells. Stable carrier cultures could be obtained from L cells infected with VSV-sp at low multiplicities without pretreatment with interferon. This may be related to the fact that VSV-sp is more sensitive to interferon than either VSV-mp or VSV-o., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-40-2-481