1887

Abstract

SUMMARY

This paper is a report of studies on Cotia virus; this had been first isolated in 1965 in Brazil and was subsequently shown to be a poxvirus.

Cotia virus grew in a wide range of cell cultures and on the chick chorioallantois (CAM). Its growth characteristics are similar to those of other poxviruses. Microscopy showed virus factories or type B inclusions appearing before infectious progeny virus could be demonstrated. Type A inclusions appeared later, after development of progeny virus; these were shown by electron microscopy to differ from the type A inclusions of cowpox and other poxviruses and they have been termed Cotia bodies. Immunofluorescent staining also showed ring structures which appeared before the development of Cotia bodies. The growth of Cotia virus in human embryo lung (HEL) cells was sensitive to inhibitors of DNA and protein synthesis but was resistant to a concentration of rifampicin which inhibited vaccinia virus. Sharing of antigens between the Cotia virus and vaccinia virus was shown by gel precipitation tests and immunofluorescent staining. There was no cross neutralization between Cotia virus and vaccinia virus nor did anti-Cotia sera neutralize representatives of other poxvirus groups.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-40-2-263
1978-08-01
2024-03-29
Loading full text...

Full text loading...

/deliver/fulltext/jgv/40/2/JV0400020263.html?itemId=/content/journal/jgv/10.1099/0022-1317-40-2-263&mimeType=html&fmt=ahah

References

  1. Ando N., Matumoto M. 1970; Unmasking of growth of dermovaccinia strain Dairen I in L cells by acid treatment of cells after virus adsorption. Japanese Journal of Microbiology 14:181–186
    [Google Scholar]
  2. Arhelger R. B., Randall C. C. 1964; Electron microscopic observations on the development of fowl-pox virus in chorioallantoic membrane. Virology 22:59–66
    [Google Scholar]
  3. Dales S., Siminovitch L. 1961; The development of vaccinia virus in Earle’s L strain cells as examined by electron microscopy. Journal of Biophysical and Biochemical Cytology 10:475–503
    [Google Scholar]
  4. Datt N. S., Orlans E. S. 1958; The immunological relationship of the vaccinia and pig pox viruses demonstrated by gel diffusion. Immunology 1:81–86
    [Google Scholar]
  5. De Boer G. F. 1975; Swinepox. Virus isolation, experimental infections and the differentiation from vaccinia virus infections. Archives of Virology 49:141–150
    [Google Scholar]
  6. De Souza Lopes O., Lacerda J. P. G., Fonseca I. E. M., Castro D. P., Forattini O. P., Rabello E. X. 1965; Coda virus: a new agent isolated from sentinel mice in Sao Paulo, Brazil. American Journal of Tropical Medicine and Hygiene 14:156–157
    [Google Scholar]
  7. Ichihashi Y., Matsumoto S. 1966; Studies on the nature of Marchal bodies (A-type inclusion) during ectromelia virus infection. Virology 29:264–275
    [Google Scholar]
  8. Ichihashi Y., Matsumoto S. 1968; The relationship between poxvirus and A-type inclusion body during double infection. Virology 36:262–270
    [Google Scholar]
  9. Joklik W. K. 1962; The purification of four strains of poxvirus. Virology 18:9–18
    [Google Scholar]
  10. Kamahora J., Kato S., Baba E., Hagiwara K. 1955; Studies on the inclusion bodies of fowlpox virus. Medical Journal of Osaka University 6:745–754
    [Google Scholar]
  11. Kameyama S., Takahashi M., Toyoshima K., Kato S., Kamahora J. 1959; Studies on the inclusion bodies of ectromelia virus using the fluorescent antibody technique. Biken’s Journal 2:341–344
    [Google Scholar]
  12. Kato S., Hagiwara K., Kamahora J. 1955; The mechanism of the growth of ectromelia virus propagated in the ascites tumor cells. I. Study on the inclusion bodies of ectromelia virus. Medical Journal of Osaka University 6:39–50
    [Google Scholar]
  13. Kato S., Hara J., Ogawa M., Miyamoto H., Kamahora J. 1963; Inclusion markers of cowpox virus and alastrim virus. Biken’s Journal 6:233–235
    [Google Scholar]
  14. Kato S., Takahashi M., Kameyama S., Kamahora J. 1959a; A study on the morphological and cyto-immunological relationship between the inclusions of variola, cowpox, rabbitpox, vaccinia (variola origin) and vaccinia IHD and a consideration of the term ‘Guarnieri body’. Biken’s Journal 2:353–363
    [Google Scholar]
  15. Kato S., Takahashi M., Kameyama S., Kamahora J. 1959b; A study of new inclusion bodies of cowpox virus. Biken’s Journal 2:93–96
    [Google Scholar]
  16. Matsumoto S. 1958; Electron microscope studies of ectromelia virus multiplication. Annual Report of the Institute for Virus Research, Kyoto University 1:151–184
    [Google Scholar]
  17. Purcell D. A., Clarke J. K., Mcferran J. B., Hughes D. A. 1972; The morphogenesis of pigeonpox virus. Journal of General Virology 15:79–83
    [Google Scholar]
  18. Stim T. B. 1969; Arbovirus plaquing in two simian kidney cell lines. Journal of General Virology 5:329–338
    [Google Scholar]
  19. Tajima M., Ushijima T. 1966; Electron microscopy of avian pox viruses with special reference to the significance of inclusion bodies in viral replication. Japanese Journal of Veterinary Science 28:107–118
    [Google Scholar]
  20. Takahashi M., Kameyama S., Kato S., Kamahora I. 1959; The immunological relationship of the poxvirus group. Biken’s Journal 2:27–29
    [Google Scholar]
  21. Theiler M., Downs W. A. 1973; Ungrouped viruses. In The Arthropod-borne Viruses of Vertebrates pp. 335 Edited by Theiler M., Downs W. G. New Haven & London: Yale University Press;
    [Google Scholar]
  22. Tsuruhara T. 1971; Immature particle formation of Yaba poxvirus studied by electron microscopy. Journal of the National Cancer Institute 47:549–554
    [Google Scholar]
  23. Ueda Y., Tagaya I., Shiroki K. 1968; Immunological relationship between herpes simplex virus and B virus. Archiv für die gesamte Virusforschung 24:231–244
    [Google Scholar]
  24. Ueda Y., Ito M., Tagaya L. 1969; A specific surface antigen induced by poxvirus. Virology 38:180–182
    [Google Scholar]
  25. Ueda Y., Tagaya L., Amano H., Ito M. 1972; Studies on the early antigens induced by vaccinia virus. Virology 49:794–800
    [Google Scholar]
  26. Woodroofe G. M., Fenner F. 1962; Serological relationships within the poxvirus group: an antigen common to all members of the group. Virology 16:334–341
    [Google Scholar]
  27. Yoshii T., Kono R. 1977; Establishment of a rabbit lung cell line (RL-33) and its viral susceptibility. Japanese Journal of Medical Science & Biology 30:149–157
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-40-2-263
Loading
/content/journal/jgv/10.1099/0022-1317-40-2-263
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error