1887

Abstract

Summary

Injection of single precipitin bands (from immunodiffusion tests) into the lymph nodes of rabbits produced antisera reacting in immunodiffusion tests with individual specific antigens of herpes simplex virus. Antisera were made to an antigen obtained by preparative electrophoresis of an extract of cells infected with herpes; neutralization of the infectivity of herpes virus was demonstrated. An antiserum was also prepared to the antigen common to extracts of cells infected with herpes and pseudorabies virus; it contained no neutralizing antibody.

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/content/journal/jgv/10.1099/0022-1317-4-2-163
1969-03-01
2024-04-23
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References

  1. Dulbecco R., Vogt M. 1954; Plaque formation and isolation of pure lines with poliomyelitis viruses. J. exp. Med 99:167
    [Google Scholar]
  2. Goudie R. B., Horne C. H. W., Wilkinson P. C. 1966; A simple method for producing antibody specific to a single selected diffusible antigen. Lancet 2:1224
    [Google Scholar]
  3. Ross L. J. N., Watson D. H., Wildy P. 1968; Development and localization of virus-specific antigens during the multiplication of herpes simplex virus in BKH 21 cells. J. gen. Virol 2:115
    [Google Scholar]
  4. Russell W. C. 1962; A sensitive and precise plaque assay for herpes virus. Nature, Lond 195:1028
    [Google Scholar]
  5. Smith H., Gallop R. C., Tozer B. T. 1964; The production of specific rabbit antibodies by injecting antigen-antibody complexes separated from mixed antigens. Immunology 7:111
    [Google Scholar]
  6. Watson D. H. 1969; The separation of herpes virus specific antigens by polyacrylamide gel electrophoresis. J. gen. Virol 4:151
    [Google Scholar]
  7. Watson D. H., Wildy P., Harvey B. A. M., Shed den W. I. H. 1967; Serological relationships amongst viruses of the herpes group. J. gen. Virol 1:139
    [Google Scholar]
  8. Watson D. H., Shedden W. I. H., Elliot A., Tetsuka T., Wildy P., Bourgaux-Ramoisy D., Gold E. 1966; Virus specific antigens in mammalian cells infected with herpes simplex virus. Immunology 11:399
    [Google Scholar]
  9. Wildy P., Russell W. C., Horne R. W. 1960; The morphology of herpes virus. Virology 12:204
    [Google Scholar]
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