@article{mbs:/content/journal/jgv/10.1099/0022-1317-39-2-387, author = "Halbach, Michael and Koschel, Klaus and Jungwirth, Christoph", title = "Interferon Enhances the Fragility of Lysosomes in L-929 Mouse Fibroblasts", journal= "Journal of General Virology", year = "1978", volume = "39", number = "2", pages = "387-390", doi = "https://doi.org/10.1099/0022-1317-39-2-387", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-39-2-387", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", abstract = "SUMMARY Infection of interferon-treated L-929 mouse fibroblasts with vaccinia WR virus is followed by severe cytolysis within 3 to 4 h. It is shown that this cytolysis cannot be caused by enzymes released from lysosomes into the cytosol. However, there is evidence that homologous interferon has a noxious effect on lysosomes. This phenomenon appears to be another aspect of the anticellular functions of interferon.", }