1887

Abstract

SUMMARY

Two new virus isolates, M432 and M832, obtained from the Southeast Asian mouse have been characterized morphologically with respect to their composition and intracellular assembly. The mature virions resemble in certain respects the type B murine retroviruses. The new isolates, however, have an intracellular precursor, a type A particle, closely associated with the mitotic apparatus. The intracellular transport of the type A particles to the cell surface, where they are released by budding, is closely associated with the microtubule system of the cell.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-39-1-41
1978-04-01
2024-12-14
Loading full text...

Full text loading...

/deliver/fulltext/jgv/39/1/JV0390010041.html?itemId=/content/journal/jgv/10.1099/0022-1317-39-1-41&mimeType=html&fmt=ahah

References

  1. Bernhard W. 1973; Oncorna viruses 2. Type A and C virus particles in murine and other mammalian leukemias and sarcomas. In Ultrastructure of Animal Viruses and Bacteriophages. An Atlas p 283 Edited by Dalton A. J., Haguenau F. New York and London: Academic Press;
    [Google Scholar]
  2. Callahan R., Benveniste R. E., Sherr C. J., Schidlovsky G., Todaro G. J. 1976; A new class of genetically transmitted retravirus isolated from Mus cervicolor. Proceedings of the National Academy of Sciences of the United States of America 73:3579–3583
    [Google Scholar]
  3. Callahan R., Sherr C. J., Todaro G. J. 1977; A new class of murine retroviruses: immunological and biochemical comparison of novel isolates from Mus cervicolor and Mus caroli. Virology 80:401–416
    [Google Scholar]
  4. Dahlberg J. E., Perk K., Dalton A. J. 1974; Virus-like particles induced in guinea pig cells by 5-bromo-2′-deoxyuridine are morphologically similar to murine B-type virus. Nature, London 249:828–830
    [Google Scholar]
  5. Dalton A. J., Melnick J. L., Bauer H., Beaudreau G., Bentvelzen P., Bolognesi D., Gallo R., Graffi A., Haguenau F., Heston W., Huebner R., Todaro G., Heine U. I. 1974; The Case for a family of reverse transcriptase viruses: Retraviridae. Intervirology 4:201–206
    [Google Scholar]
  6. Ehrlich H. P., Bornstein P. 1973; Microtubules in transcellular movement of procollagen. Nature New Biology 238:257–260
    [Google Scholar]
  7. Gould R. R., Borisy G. G. 1976; Discrete particles at the centrosomes and kinetochores of Chinese hamster ovary cells. Journal of Cell Biology 70:43a
    [Google Scholar]
  8. Gould R. R., Borisy G. G. 1977; The pericentriolar material in Chinese hamster ovary cells nucleates microtubule formation. Journal of Cell Biology 73:601–615
    [Google Scholar]
  9. Hartley J. W., Rowe W. P. 1976; Naturally occurring murine leukemia virus in wild mice: characterization of a new ‘amphotropic’ class. Journal of Virology 19:19–25
    [Google Scholar]
  10. Heine U. 1969; Electron microscopic studies on HeLa cells exposed to the antibiotic toyocamycin. Cancer Research 29:1875–1880
    [Google Scholar]
  11. Jainchill J. R., Aaronson S. A., Todaro G. J. 1969; Murine sarcoma and leukaemia viruses: assay using clonal lines of contact inhibited cells. Journal of Virology 4:549–553
    [Google Scholar]
  12. Lacy P. E., Howell S. L., Young D. A., Fink C. J. 1968; New hypothesis of insulin secretion. Nature, London 219:1177–1179
    [Google Scholar]
  13. Lemarchand Y., Single A., Assimacoupolus-Jeannet F., Orci L., Rouiller C., Jeanrenard B. 1973; A role for the microtubular system in the release of very low density lipoproteins by perfused mouse liver. Journal of Biological Chemistry 248:6862–6870
    [Google Scholar]
  14. Lieber M. M., Benveniste R. E., Livingston D. M., Todaro G. J. 1973; Mammalian cells in culture frequently release type C viruses. Science 182:56–59
    [Google Scholar]
  15. Michalides R., Schlom J., Dahlberg J., Perk K. 1975; Biochemical properties of the bromodeoxy-uridine-induced guinea pig virus. Journal of Virology 16:1039–1050
    [Google Scholar]
  16. Moore D. H. 1962; On the identification and characterization of the milk agent. In Tumor Viruses of Murine Origin p 107 Edited by Wolstenholme G. E. W., O’Connor M. Boston: Little, Brown and Co;
    [Google Scholar]
  17. Porter K. R. 1973; Microtubules in intracellular locomotion. In Locomotion of Tissue Cells (Ciba Foundation Symposium 14), p 149 North-Holland, Amsterdam: Elsevier, Excerpta Medica;
    [Google Scholar]
  18. Sasaki S., Tashiro Y. 1976; Studies on the posterior silk gland of the silkworm Bombyx mori. VI. Distribution of microtubules in the posterior silk gland cells. Journal of Cell Biology 71:565–574
    [Google Scholar]
  19. Stubblefield F., Klevecz R. R. 1965; Synchronization of Chinese hamster cells by reversal of Colcemid inhibition. Experimental Cell Research 40:660–664
    [Google Scholar]
  20. Tanaka H. 1977; Precursor-product relationship between nonglycosylated polypeptides of A and B particles of mouse mammary tumor virus. Virology 76:835–850
    [Google Scholar]
  21. Wheatley D. N. 1974; Pericentriolar virus-like particles in Chinese hamster ovary cells. Journal of General Virology 24:395–399
    [Google Scholar]
/content/journal/jgv/10.1099/0022-1317-39-1-41
Loading
/content/journal/jgv/10.1099/0022-1317-39-1-41
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error