1887

Abstract

SUMMARY

A solid-phase radioimmunoassay for antibodies to hepatitis B core antigen (anti-HB) is described. Polystyrene beads coated with anti-HB, hepatitis B core antigen prepared from pooled sera of humans infected with hepatitis B virus (HBV) and I-labelled anti-HB were used for the test.

Distinct patterns of development and changes of anti-HB and their immunologic properties are all related to variations of other markers specific for HBV infections. Knowledge concerning the detailed features of the immune response to hepatitis B core antigen may provide deeper insight into the pathogenesis of HBV infections.

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1978-03-01
2022-01-19
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