RT Journal Article SR Electronic(1) A1 Shiraishi, H. A1 Shirachi, R. A1 Ishida, N. A1 Sekine, T.YR 1978 T1 The Specific Reduction of a and d Antigenic Determinants after Periodate Treatment of Hepatitis B Surface Antigen (HBsAg) JF Journal of General Virology, VO 38 IS 2 SP 363 OP 367 DO https://doi.org/10.1099/0022-1317-38-2-363 PB Microbiology Society, SN 1465-2099, AB SUMMARY HBsAg antigenicity was found to be sensitive to periodate treatment. Antigenic determinants a and d were especially sensitive, losing almost all of their activity, while determinants r and w were found to be quite stable. Also, it is now possible to prepare the monospecific antibodies, anti-r and anti-w, by the use of this new, simpler procedure., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-38-2-363