1887

Abstract

SUMMARY

Three polypeptides with mol. wt. 100 (P100), 80 (P80) and 65 (P65) × 10 were found in calicivirus infected cells. P100 and P80 were present in sub-molar amounts compared with P65 and no precursor product relationship between the three polypeptides could be demonstrated using pulse-chase experiments or selective inhibitors of protein synthesis and of proteases. In the presence of protease inhibitors a polypeptide with mol. wt. 120 × 10 (P120) was demonstrated which appeared to be the precursor of P100. Possible mechanisms of translation in the caliciviruses are discussed.

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1978-01-01
2024-04-19
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