An Assessment by Competition Hybridization of the Sequence Homology between the RNAs of the Seven Serotypes of FMDV Free

Abstract

Summary

A comparison has been made of the RNAs of the seven serotypes of foot-and-mouth disease virus (FMDV) by competition hybridization. Homology among the three European serotypes A, O, C and the Asia 1 serotype was 60 to 70%. Similar homologies were found among the three Southern African Territories serotypes (SAT 1, SAT 2, SAT 3), but homology between the two groups was much lower (25 to 40%). Homology between the RNAs of subtypes within serotypes A and O was greater than 70%. Double competition experiments with the European serotypes indicate sharing of nucleotide sequences.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-37-2-271
1977-11-01
2024-03-28
Loading full text...

Full text loading...

/deliver/fulltext/jgv/37/2/JV0370020271.html?itemId=/content/journal/jgv/10.1099/0022-1317-37-2-271&mimeType=html&fmt=ahah

References

  1. Brooksby J. B. 1958; The virus of foot-and-mouth disease. Advances in Virus Research 5:1–37
    [Google Scholar]
  2. Darby G., Minson A. C. 1973; The structure of tobacco rattle virus ribonucleic acids: common nucleotide sequences in the RNA species. Journal of General Virology 49:285–295
    [Google Scholar]
  3. Dietzschold B., Kaaden O. R., Ahl R. 1972; Hybridization studies with subtypes and mutants of foot-and-mouth disease virus type O. Journal of General Virology 15:171–174
    [Google Scholar]
  4. Dietzschold B., Kaaden O. R., Tokui T., Bohm H. O. 1971; Polynucleotide sequence homologies among RNAs of foot-and-mouth disease virus types A, C & O. Journal of General Virology 13:1–7
    [Google Scholar]
  5. Eisenthal R., Cornish-Bowden A. 1974; The direct linear plot. A new graphical procedure for estimating enzyme kinetic parameters. The Biochemical Journal 139:715–720
    [Google Scholar]
  6. Harris T. J. R., Brown F. 1977; Biochemical analysis of a virulent and an avirulent strain of foot-and-mouth disease virus. Journal of General Virology 34:87–105
    [Google Scholar]
  7. Sangar D. V., Black D. N., Rowlands D. J., Brown F. 1977; Biochemical mapping of the foot-and-mouth disease virus genome. Journal of General Virology 35:281–297
    [Google Scholar]
  8. Young N. A., Hoyer B. H., Martin M. A. 1968; Polynucleotide sequence homologies among polioviruses. Proceedings of the National Academy of Sciences of the United States of America 61:548–555
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-37-2-271
Loading
/content/journal/jgv/10.1099/0022-1317-37-2-271
Loading

Data & Media loading...

Most cited Most Cited RSS feed