1887

Abstract

Summary

Two morphological types of human rotavirus particles were separated in caesium chloride density gradients. The particles of higher density (‘incomplete’ particles without an outer capsid layer) banded at a density of 1.38 g/ml, while the less dense (‘complete’ particles with an outer as well as an inner capsid layer) banded at a density of 1.36 g/ml. Some particles were found with an incomplete outer layer of capsomeres. The particle/infectivity ratio for tissue cultures of the fraction containing complete particles was more than 3 log higher than that of the fraction containing incomplete particles. But, as there was a small number of complete particles in the fraction containing mostly incomplete particles, it was impossible to determine whether the incomplete particles had a low infectivity or whether they had none at all.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-37-1-191
1977-10-01
2019-11-18
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-37-1-191
Loading

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error