The Effect of Temperature on the Synthesis of Rhinovirus Type 2 RNA Free

Abstract

SUMMARY

The reduced yields of rhinovirus type 2 at temperatures above 37 °C were shown to result from the degradation of virus-induced RNA, leaving little RNA available for inclusion into mature infectious virions. The degradation occurred about 6 h p.i., and appeared to be selectively effecting the single-stranded species. Lysosomal nucleases do not appear to have a role in this supra-optimal degradation.

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1977-09-01
2024-03-29
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