1887

Abstract

SUMMARY

A study, using the Rhode Island Red (RIR) strain of fowl maintained at Houghton Poultry Research Station, was made to investigate the genetic control of cellular response to infection with viruses of subgroups A and C. Family matings within the RIR strain and test-crosses between the RIR parents and White Leghorn (WL) parents of known genotype were set up to ascertain linkage between the tumour virus () and tumour virus () loci.

The results confirmed that in this RIR strain, the two loci, and , control the cellular response to viruses of subgroups A and C, respectively, as reported in other breeds of fowl (WL and New Hampshire). As in WL fowl, the two loci are linked. The linkage value of 0.22 in the male sex agreed well with that reported in the WL male sex, indicating that the two loci are located in the same sites in homologous chromosomes in the two breeds. However, in the RIR strain, no sex difference in crossing over between the two linked loci was found, contrary to that reported in WL fowl where the absence of crossing over between the two loci was observed in the heterogametic female sex.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-35-1-13
1977-04-01
2022-01-22
Loading full text...

Full text loading...

/deliver/fulltext/jgv/35/1/JV0350010013.html?itemId=/content/journal/jgv/10.1099/0022-1317-35-1-13&mimeType=html&fmt=ahah

References

  1. Biggs P. M., Payne L. N. 1967; Studies in Marek’s disease. I. Experimental transmission. Journal of the National Cancer Institute 39:267–280
    [Google Scholar]
  2. Cotterman C. W. 1964 In Statistics and Mathematics in Biology chapter 35 New York: Hafner Publishing Company;
  3. Crittenden L. B., Motta J. V. 1969; A survey of genetic resistance to leuko-sarcoma virus in commercial stocks of chickens. Poultry Science 48:1751–1752
    [Google Scholar]
  4. Fisher R. A. 1935; The detection of linkage with ‘dominant’ abnormalities. Annals of Eugenics 6:187–201
    [Google Scholar]
  5. Hutt F. B. 1949 In Genetics of the Fowl chapter 14 pp 486–498 London: McGraw-Hill;
    [Google Scholar]
  6. Lush J. L. 1948 In The Genetics of Population pp 40–62 Ames, Iowa: Mimeograph;
    [Google Scholar]
  7. Mather K. 1951 In The Measurement of Linkage in Heredity 2nd edition pp 114–122 London: Methuen;
    [Google Scholar]
  8. Motta J. V., Crittenden L. B., Pollard W. O. 1973; The inheritance of resistance to subgroup C leukosis-sarcoma virus in New Hampshire Chickens. Poultry Science 52:578–586
    [Google Scholar]
  9. Pani P. K. 1974a; Close linkage between genetic loci controlling response of fowl to subgroup A and subgroup C sarcoma viruses. Journal of General Virology 22:187–195
    [Google Scholar]
  10. Pani P. K. 1974b; No crossing over between closely linked tumour virus loci in the heterogametic sex of fowl. Nature, London 242:592–594
    [Google Scholar]
  11. Pani P. K. 1976; Genetics of resistance of fowl to infection by RNA tumour viruses. Proceedings of the Royal Society of Medicine 69:43–48
    [Google Scholar]
  12. Pani P. K., Biggs P. M. 1973; Genetic control of susceptibility to an A subgroup sarcoma virus in commercial chickens. Avian Pathology 21:27–41
    [Google Scholar]
  13. Pani P. K., Biggs P. M. 1974; Heritability and number of genes controlling susceptibility of chick embryo chorioallantoic membranes (CAM) to RSV. Avian Pathology 3:115–122
    [Google Scholar]
  14. Pani P. K., Payne L. N. 1973; Further evidence for two loci which control susceptibility of fowl to RSV(RAV-O). Journal of General Virology 19:235–244
    [Google Scholar]
  15. Payne L. N. 1971; Interaction between host genes and avian RNA tumour viruses. In RNA Viruses and Host Genome in Oncogenesis pp. 93–112 Edited by Emmelot P., Bentvelzen P. Amsterdam, London: North Holland Publishing Co;
    [Google Scholar]
  16. Payne L. N., Biggs P. M. 1966; Genetic basis of cellular susceptibility to the Schmidt-Ruppin and Harris strains of Rous sarcoma virus. Virology 29:190–198
    [Google Scholar]
  17. Payne L. N., Biggs P. M. 1970; Genetic resistance of fowl to MH2 reticuloendothelioma virus. Journal of General Virology 7:177–185
    [Google Scholar]
  18. Payne L. N., Pani P. K. 1971; Evidence for linkage between genetic loci controlling response of fowl to subgroup A and subgroup C sarcoma viruses. Journal of General Virology 13:253–259
    [Google Scholar]
  19. Payne L. N., Pani P. K., Weiss R. A. 1971; A dominant gene which inhibits cellular susceptibility to RSV(RAV-O). Journal of General Virology 13:455–462
    [Google Scholar]
  20. Taylor L. W. 1934; Creeper and Single-Comb linkage in the fowl. Journal of Heredity 25:205–206
    [Google Scholar]
  21. Temin H. M., Rubin H. 1958; Characteristics of an assay of Rous sarcoma virus and Rous sarcoma cells in tissue culture. Virology 6:669–688
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-35-1-13
Loading
/content/journal/jgv/10.1099/0022-1317-35-1-13
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error