1887

Abstract

SUMMARY

It has been found by immune electron microscopy that rotavirus-infected faeces, calf or human, contain an antigenic subunit associated with the inner of the two virus capsids. This internal component represents the group specific antigen for the rotavirus group and the subunit reacts with both homologous and heterologous antiserum. It can therefore be used in diagnostic tests and in this paper its use as a reagent for immunodiffusion is described.

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/content/journal/jgv/10.1099/0022-1317-34-2-325
1977-02-01
2021-10-20
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References

  1. Almeida J. D. 1976; Immune complexes as seen by electron microscopy. Supplement to Annals of Rheumatic diseases (in the press)
    [Google Scholar]
  2. Almeida J. D., Stannard L. M., Pennington T. H. 1965; A simple dark ground method for the recording of gel diffusions. Archiv für die Gesamte Virusforschung 17:330–334
    [Google Scholar]
  3. Almeida J. D., Waterson A. P. 1975; Hepatitis B antigen - an incomplete history. American Journal of the Medical Sciences 370:105–114
    [Google Scholar]
  4. Almeida J. D., Zuckerman A. J. 1976; The importance of being rotavirus. Nature, London 360:393
    [Google Scholar]
  5. Davidson G. P., Bishop R. F., Townley R. R. W., Holmes I. H., Ruck B. J. 1975; Importance of a new virus in acute sporadic enteritis in children. Lancet 1:242–246
    [Google Scholar]
  6. Fernelius A. L., Ritchie A. E., Classick L. G., Norman J. O., Mebus C. A. 1972; Cell culture adaptation and propagation of a reovirus-like agent of calf diarrhoea from a field outbreak in Nebraska. Archiv für die Gesamte Virus forschung 37:114–130
    [Google Scholar]
  7. Flewett T. H., Davies H., Bryden A. S., Robertson M. J. 1974a; Diagnostic electron microscopy of faeces. Ⅱ. Acute gastroenteritis associated with reovirus-like particles. Journal of Clinical Pathology 27:603–614
    [Google Scholar]
  8. Flewett T. H., Bryden A. S., Davies H., Woode G. N., Bridger J. C., Derrick J. M. 1974b; Relation between viruses from acute gastroenteritis of children and newborn calves. Lancet ii:61–63
    [Google Scholar]
  9. Kapikian A. Z., Kim H. W., Wyatt R. G., Rodriguez W. J., Ross S., Cline W. L., Parrott R. H., Chanock R. M. 1974; Reovirus-like agent in stools: association with infantile diarrhoea and development of serologic tests. Science 185:1049–1053
    [Google Scholar]
  10. Kapikian A. Z., Cline W. L., Mebus C. A., Wyatt R. G., Kalica A. R., James H. D., Vankirk D., Chanock R. M., Kim H. W. 1975; New complement-fixation test for the human reovirus-like agent of infantile gastroenteritis. Lancet I:1056–1061
    [Google Scholar]
  11. Martin M. L., Erskine L., Palmer E. L., Middleton P. J. 1975; Ultrastructure of infantile gastroenteritis virus. Virology 68:146–153
    [Google Scholar]
  12. Prince A. M. 1968; An antigen detected in the blood during the incubation period of serum hepatitis. Proceedings of the National Academy of Sciences of the United States of America 60:816
    [Google Scholar]
  13. Rotaviruses of man and animals. 1975 Lancet leader article i:257–259
    [Google Scholar]
  14. Woode G. N., Bridger J. C., Jones J. M., Flewett T. H., Bryden A. S., Davies H. A., White G. B. B. 1976; Morphological and antigenic relationships between viruses (rotaviruses) from acute gastroenteritis of children, calves, piglets, mice and foals. Infection and Immunity (in the press)
    [Google Scholar]
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