RT Journal Article SR Electronic(1) A1 Turner, G. S.YR 1976 T1 Thymus Dependence of Rabies Vaccine JF Journal of General Virology, VO 33 IS 3 SP 535 OP 538 DO https://doi.org/10.1099/0022-1317-33-3-535 PB Microbiology Society, SN 1465-2099, AB SUMMARY Immune responses to rabies vaccine were compared with those to known thymus-dependent and thymus-independent antigens, in nude mice and their normal litter mates. No antibody response to, or protection against, challenge was observed in nude mice inoculated with either 1 or 2 doses of rabies vaccine. A single dose of the same vaccine induced a substantial antibody response and protected normal mice. These data indicate that the antigens in rabies vaccine that induce neutralizing antibody and protect mice are thymus-dependent., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-33-3-535