1887

Abstract

Summary

The Stokes radius of unpurified hepatitis B antigen (HBAg) was determined by chromatography on a carefully calibrated Sepharose 4B column. A value of 14.2 nm was found by this procedure, contrasting with a published value of 11 nm for purified, pepsin-treated HBAg. Chromatography at pH 3 appeared to reduce the Stokes radius of HBAg to 11 nm. Evidence is presented to show that serum proteins adsorbed to HBAg can be removed with pepsin or acid.

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/content/journal/jgv/10.1099/0022-1317-33-2-345
1976-11-01
2019-11-13
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-33-2-345
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