1887

Abstract

SUMMARY

Serial high multiplicity passage of a cloned stock of vesicular stomatitis virus was found to generate defective interfering particles containing three size classes of RNA, with sedimentation coefficients of 31S, 23S and 19S. The 31S and 23S RNA species were found to be complementary to both the 12 to 18S and 31S size classes of VSV mRNAs. The 19S class of RNA was found to be partially base-paired. All three RNA species were found to contain ppAp at their 5′ termini.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-33-1-51
1976-10-01
2024-04-16
Loading full text...

Full text loading...

/deliver/fulltext/jgv/33/1/JV0330010051.html?itemId=/content/journal/jgv/10.1099/0022-1317-33-1-51&mimeType=html&fmt=ahah

References

  1. Abraham G., Rhodes D. P., Banerjee A. K. 1975; The 5′-terminal structure of the methylated mRNA synthesized in vitro by vesicular stomatitis virus. Cell 5:51–58
    [Google Scholar]
  2. Banerjee A. K., Moyer S. A., Rhodes D. P. 1974; Studies on the in vitro adenylation of RNA by vesicular stomatitis virus. Virology 61:547–558
    [Google Scholar]
  3. Baltimore D. 1971; Expression of animal virus genomes. Bacteriological Reviews 35:235–241
    [Google Scholar]
  4. Crick J., Cartwright B., Brown F. 1969; A study of the interference phenomenon in vesicular stomatitis virus replication. Archiv fiir die Gesamte Virusforschung 27:221–235
    [Google Scholar]
  5. Hefti E., Bishop D. H. L. 1975; The 5′-nucleotide sequence of vesicular stomatitis viral RNA. Journal of Virology 15:90–96
    [Google Scholar]
  6. Huang A. S. 1973; Defective interfering viruses. Annual Review of Microbiology 27:101–117
    [Google Scholar]
  7. Huang A. S., Baltimore D. 1970; Defective viral particles and viral disease. Nature, London 226:325–327
    [Google Scholar]
  8. Huang A. S., Greenawalt J. W., Wagner R. R. 1966; Defective T particles of vesicular stomatitis virus.1. Preparation, morphology, and some biologic properties. Virology 30:161–172
    [Google Scholar]
  9. Huang A. S., Wagner R. R. 1966a; Defective T particles of vesicular stomatitis virus. II. Biological role in homologous interference. Virology 30:173–181
    [Google Scholar]
  10. Huang A. S., Wagner R. R. 1966b; Comparative sedimentation coefficients of RNA extracted from plaque–forming and defective particles of vesicular stomatitis virus. Journal of Molecular Biology 22:381–384
    [Google Scholar]
  11. Krontiris T. G., Soeiro R., Fields B. N. 1973; Host restriction of Friend leukemia, virus - role of the viral outer coat. Proceedings of the National Academy of Sciences of the United States of America 70:2549–2553
    [Google Scholar]
  12. Lazzarrini R. A., Weber G. H., Johnson L. D., Stamminger G. M. 1976; Covalently linked message and anti-message (genomic) RNA from a defective vesicular stomatitis virus particle. Journal of Molecular Biology (in the press)
    [Google Scholar]
  13. Leamnson R. N., Reichmann M. E. 1974; The RNA of defective vesicular stomatitis virus particles in relation to viral cistrons. Journal of Molecular Biology 85:551–568
    [Google Scholar]
  14. Moyer S. A., Abraham G., Adler R., Banerjee A. K. 1975; Methylated and blocked 5′ termini in vesicular stomatitis virus in vivo mRNAs. Cell 5:59–67
    [Google Scholar]
  15. Moyer S. A., Banerjee A. K. 1975; Messenger RNA species synthesized in vitro by the virion-associated RNA polymerase of vesicular stomatitis virus. Cell 4:37–43
    [Google Scholar]
  16. Mudd J. A., Summers D. F. 1970; Polysomal ribonucleic acid of vesicular stomatitis virus-infected HeLa cells. Virology 42:958–968
    [Google Scholar]
  17. Petric M., Prevec L. 1970; Vesicular stomatitis virus - a new interfering particle, intracellular structures, and virus–specific RNA. Virology 41:615–630
    [Google Scholar]
  18. Reichmann M. E., Pringle C. R., Follet E. A. C. 1971; Defective particles in BHK cells infected with temperature-sensitive mutants of vesicular stomatitis virus. Journal of Virology 6:604–609
    [Google Scholar]
  19. Roy P., Bishop D. H. L. 1971; Nucleoside triphosphate phosphotransferase - a new enzyme activity of oncogenic and non-oncogenic ‘budding’ viruses. Biochimica et Biophysica Acta 235:191–206
    [Google Scholar]
  20. Roy P., Hefti R., Bishop D. H. L. 1973; Complementary RNA species isolated from vesicular stomatitis (HR strain) defective virions. Journal of Virology 11:915–925
    [Google Scholar]
  21. Schaffer F. L., Hackett A. J., Soergel M. E. 1968; Vesicular stomatitis virus RNA: complementarity between infected cells RNA and RNA’s from infectious and autointerfering fractions. Biochemical and Biophysical Research Communications 31:685–692
    [Google Scholar]
  22. Stamminger G., Lazzarrini R. A. 1974; Analysis of RNA of defective VSV particles. Cell 3:85–93
    [Google Scholar]
  23. Stampfer M., Baltimore D., Huang A. S. 1969; Ribonucleic acid synthesis of vesicular stomatitis virus. 1. Species of ribonucleic acid found in Chinese hamster ovary cells infected with plaque-forming and defective particles. Journal of Virology 4:154–161
    [Google Scholar]
  24. Wagner R. R. 1975; Reproduction of rhabdoviruses. In Comprehensive Virology vol 4 pp 1–80 Edited by Fraenkel-Conrat H., Wagner R. R. New York, New York: Plenum Press;
    [Google Scholar]
  25. Wild T. F. 1972; Replication of vesicular stomatitis virus: the effect of purified interfering component. Journal of General Virology 17:295–305
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-33-1-51
Loading
/content/journal/jgv/10.1099/0022-1317-33-1-51
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error