%0 Journal Article %A Stanwick, T. L. %A Kirk, B. E. %T Analysis of Baby Hamster Kidney Cells Persistently Infected with Lymphocytic Choriomeningitis Virus %D 1976 %J Journal of General Virology, %V 32 %N 3 %P 361-367 %@ 1465-2099 %R https://doi.org/10.1099/0022-1317-32-3-361 %I Microbiology Society, %X SUMMARY Baby hamster kidney cells were persistently infected with lymphocytic choriomeningitis (LCM) virus (BHKpi cells). After 21 passages of the BHKpi cells infectious virus could no longer be detected; however, the cultures continued to produce LCM virus particles which interfered with the replication of infectious LCM virus in BHKpi cells and protected mice from a subsequent intracranial inoculation of infectious LCM virus. Cultures of BHKpi cells appeared to consist of three cell populations: uninfected cells, infected cells containing infectious LCM virus, and infected cells releasing interfering particles of LCM virus. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-32-3-361