1887

Abstract

SUMMARY

Human cytomegalovirus (CMV) induces nuclear antigens resembling the Epstein-Barr nuclear antigen (EBNA) as early as 3 h after infection. These early antigens can be detected only with the anti-complement immunofluorescence staining (ACIF) technique. Synthesis of these new antigens is not influenced by cytosine arabinoside (ara-C).

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-32-2-315
1976-08-01
2021-10-24
Loading full text...

Full text loading...

/deliver/fulltext/jgv/32/2/JV0320020315.html?itemId=/content/journal/jgv/10.1099/0022-1317-32-2-315&mimeType=html&fmt=ahah

References

  1. ALBRECHT T., RAPP F. 1973; Malignant transformation of hamster embryo fibroblasts following exposure to ultraviolet-irradiated human cytomegalovirus. Virology 55:53–61
    [Google Scholar]
  2. GEDER L., VÁCZI L., JENEY E., GÖNCZÖL E., LEHEL F. 1966/67; ‘Early non-virion’ antigens in herpes simplex virus infected tissue culture cells. II. Intracellular localization of ‘early’ antigen with indirect immunofluorescence technique. Acta Microbiologica Academiae Scientiarum Hungaricae 13:365–372
    [Google Scholar]
  3. GEDER L., LAUSCH R., RAPP F., O’NEILL F. 1976; Oncogenic transformation of human embryo lung cells by human cytomegalovirus. Science, New York in the press
    [Google Scholar]
  4. JACK I., WARK M. C. 1972 Immunofiuorescent studies of the infection of fibroblastoid cells within human cytomegaloviruses. Oncogenesis & Herpesvirus339–340 Edited by Biggs P. M., de ThE G., Payne L. N. Lyon: International Agency for Research on Cancer;
    [Google Scholar]
  5. LAING A. C. 1974; Comparison of antiglobulin, direct, and anti-complement immunofiuorescent staining for the identification of cytomegalovirus in cultured human fibroblasts. Canadian Journal of Microbiology 20:1353–1248
    [Google Scholar]
  6. POPE J. H., ROWE W. P. 1964; Immunofiuorescent studies of adenovirus 12 tumors and of cells transformed or infected by adenoviruses. Journal of Experimental Medicine 120:577–587
    [Google Scholar]
  7. RAPP F., GEDER L., MURASKO D., LAUSCH R., LADDA R., HUANG E. S., WEBBER M. M. 1975; Long-term persistence of cytomegalovirus genome in cultured human cells of prostatic origin. Journal of Virology 16:982–990
    [Google Scholar]
  8. RAPP F. F., KITAHARA T., BUTEL J. S., MELNICK J. L. 1964; Synthesis of SV40 tumor antigen during replication of simian papovavirus (SV40). Proceedings of the National Academy of Sciences of the United States of America 52:1138–1142
    [Google Scholar]
  9. RAPP F., RASMUSSEN L. E., BENYESH-MELNICK M. 1963; The immunofiuorescent focus technique in studying the replication of cytomegalovirus. Journal of Immunology 91:709–719
    [Google Scholar]
  10. REEDMAN B. M., KLEIN G. 1973; Cellular localization of an Epstein-Barr virus (EBV)-associated-complement-fixing antigen in producer and non-producer lymphoblastoid cell lines. International Journal of Cancern499–520
    [Google Scholar]
  11. SABIN A. B., KOCH M. A. 1964; Source of genetic information for specific complement-fixing antigens in SV40 virus-induced tumors. Proceedings of the National Academy of Science of the United States of America 52:1131–1138
    [Google Scholar]
  12. SMITH J. D., DE HARVEN E. 1974; Herpes simplex virus and human cytomegalovirus replication in WI-38 cells. II. An ultrastructural study of viral penetration. Journal of Virology 14:945–956
    [Google Scholar]
  13. WARD R. L., STEVENS J. G. 1975; Effect of cytosine arabinoside on viral-specific protein synthesis in cells infected with herpes simplex virus. Journal of Virology 15:71–80
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-32-2-315
Loading
/content/journal/jgv/10.1099/0022-1317-32-2-315
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error