1887

Abstract

SUMMARY

Earlier results indicating that vaccinia virus entered L cells by a process of direct fusion between the virus envelope and the plasma membrane of the cell have been confirmed and extended using immuno-ferritin conjugates to locate virus antigens on the host cell surface. After fusion, components of the virus envelope become rapidly dispersed in the plasma membrane. Fusion has also been observed as the predominant mode of entry of vaccinia virus into HeLa cells.

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1976-08-01
2023-02-05
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References

  1. ARMSTRONG J. A., METZ D. H., YOUNO M. R. 1973; The mode of entry of vaccinia virus into L cells. Journal of General Virology 21:533–537
    [Google Scholar]
  2. BÁCHI T., AGUET M., HOWE C. 1973; Fusion of erythrocytes by Sendai virus studied by immuno-freeze-etching. Journal of Virology 11:1004–1012
    [Google Scholar]
  3. BLANDEN R. V. 1974; T cell responses to viral and bacterial infection. Transplantation Reviews 19:56–88
    [Google Scholar]
  4. BLANDEN R. V., DOHERTY P. C, DUNLOP M. B. C, GARDNER I. D., ZINKERNAGEL R. M., DAVID C. S. 1975; Genes required for cytotoxicity against virus-infected target cells in K and D regions of H-2 complex. Nature, London 254:269–270
    [Google Scholar]
  5. DALES S. 1965; Penetration of animal viruses into cells. Progress in Medical Virology 7:1–43
    [Google Scholar]
  6. DE PETRIS S., RAFF M. C. 1972; Distribution of immunoglobulin on the surface of mouse lymphoid cells as determined by immunoferritin electron microscopy. Antibody induced, temperature-dependent redistribution and its implications for membrane structure. European Journal of Immunology 2:523–535
    [Google Scholar]
  7. DOURMASHKIN R. R., TYRRELL D. A. J. 1970; Attachment of two myxoviruses to ciliated epithelial cells. Journal of General Virology 9:77–88
    [Google Scholar]
  8. ESTEBAN M., METZ D. H. 1973; Early virus protein synthesis in vaccinia virus infected cells. Journal of General Virology 19:201–216
    [Google Scholar]
  9. GRANADOS R. R. 1973; Entry of an insect poxvirus by fusion of the virus envelope with the host cell membrane. Virology 52:305–309
    [Google Scholar]
  10. HEINE J. W., SCHNAITMAN C. A. 1969; Fusion of vesicular stomatitis virus with the cytoplasmic membrane of L cells. Journal of Virology 3:610–622
    [Google Scholar]
  11. HEINE J. W., SCHNAITMAN C. A. 1971; Entry of vesicular stomatitis virus into L cells. Journal of Virology 8:786–795
    [Google Scholar]
  12. HIRSCH I. G., FEDORKO M. E. 1968; Ultrastructure of human leukocytes after simultaneous fixation with glutaraldehyde and osmium tetroxide, and post fixation in uranyl acetate. Journal of Cell Biology 38:615–627
    [Google Scholar]
  13. HOWE C, MORGAN C., HSU K. C. 1969 Recent virologic applications of ferritin conjugates. Progress in Medical Virology n307–353 Edited by Melnick J. L. Basel & New York: S. Karger;
    [Google Scholar]
  14. HOYLE L. 1962; The entry of myxoviruses into the cell. Cold Spring Harbor Symposia on Quantitative Biology 27:113–121
    [Google Scholar]
  15. KOHN A. 1975; The fate of protein subunits of para-influenza (Sendai) virus after adsorption to NIL8 hamster embryo cells. Journal of General Virology 29:179–188
    [Google Scholar]
  16. KOSZINOWSKI U., ERTL H. 1975; Lysis mediated by T cells and restricted by H-2 antigen of target cells infected with vaccinia virus. Nature, London 255:522–554
    [Google Scholar]
  17. MEISELMAN V., KOHN A., DANON D. 1967; Electron microscopic study of penetration of Newcastle disease virus into cells, leading to formation of polykaryocytes. Journal of Cell Science 2:71–76
    [Google Scholar]
  18. METZ D. H., ESTEBAN M. 1972; Interferon inhibits viral protein synthesis in L cells infected with vaccinia virus. Nature, London 238:385–388
    [Google Scholar]
  19. METZ D. H., ESTEBAN M., DANIELESCU G. 1975; The formation of virus polyribosomes in L cells infected with vaccinia virus. Journal of General Virology 27:181–195
    [Google Scholar]
  20. MORGAN C., HOWE C. 1968; Structure and development of viruses as observed in the electron microscope. IX. Entry of para-influenza I (Sendai) virus. Journal of Virology 2:1122–1132
    [Google Scholar]
  21. MORGAN C., ROSE H. M. 1968; Structure and development of viruses as observed in the electron microscope. VIII. Entry of influenza virus. Journal of Virology 2:925–936
    [Google Scholar]
  22. NERMUT M. V. 1973 Freeze-drying and freeze-etching of viruses. Freeze-etching Techniques and Applications135–150 Edited by Benedetti E. L., Favard P. Paris: Société Française de Microscopie Electronique;
    [Google Scholar]
  23. OKADA U., KOSERI I., KIM J., MAEDA U., HASHIMOTO T., KANNO Y., MATSUI Y. 1975; Modification of cell membranes with viral envelopes during fusion of cells with HVJ (Sendai virus). I. Interaction between cell membranes and virus in the early stages. Experimental Cell Research 93:368–378
    [Google Scholar]
  24. REYNOLDS E. S. 1963; The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. Journal of Cell Biology 17:208–212
    [Google Scholar]
  25. RUSSELL W. C, NEWMAN C., WILLIAMSON D. H. 1975; A simple cytochemical technique for demonstration of DNA in cells infected with mycoplasmas and viruses. Nature, London 253:461–462
    [Google Scholar]
  26. WESTWOOD J. C. N., HARRIS W. J., ZWARTOUW H. T., TITMUSS D. H. J., APPLEYARD G. 1964; Studies On the structure of vaccinia virus. Journal of General Microbiology 34:67–78
    [Google Scholar]
  27. WILLIAMS C. A., CHASE M. 1968 Methods in Immunology and Immunochemistry II chapter 9 135–161 New York and London: Academic Press;
    [Google Scholar]
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