@article{mbs:/content/journal/jgv/10.1099/0022-1317-32-1-133, author = "Allen, P. T. and Stewart, W. E.", title = "Evidence that Detergent-reactivated Interferons are not Renatured", journal= "Journal of General Virology", year = "1976", volume = "32", number = "1", pages = "133-137", doi = "https://doi.org/10.1099/0022-1317-32-1-133", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-32-1-133", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", abstract = "SUMMARY The sedimentation rate of human leukocyte interferon (HLIF) reactivated from sodium dodecyl sulphate (SDS) solution was studied by glycerol gradient centrifugation and compared to that of native HLIF. Reactivated HLIF consistently sedimented faster than native HLIF, indicating that full recovery of antiviral activity does not require renaturation of the entire interferon molecule.", }