1887

Abstract

SUMMARY

The action of two restriction endonucleases on polyoma virus DNA has been examined and the sites at which they cleave the DNA located. One of the enzymes, I from OK8, cleaves polyoma DNA twice at about 11.6 and 59.2% from the RI site. The other enzyme, I from 164, cleaves polyoma DNA five times at about 14.8, 16.5, 32.6, 50.3 and 80.0% from the RI site. Some of the cleavages produced by these enzymes alone, or in conjunction with other endonucleases, may be of use in the isolation of regions of particular interest from the virus DNA.

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/content/journal/jgv/10.1099/0022-1317-31-3-315
1976-06-01
2022-06-27
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