1887

Abstract

SUMMARY

The gene 46 and 47 functions of phage T4 are required for normal DNA replication, recombination, u.v. repair and host DNA breakdown, and yet mutants defective in these genes characteristically form tiny plaques on strains lacking an suppressor. Our results imply that this limited growth is not due to misreading of codons or partial function of nearly complete polypeptides terminated at the mutation. Thus it appears that genes 46 and 47 are not entirely essential, perhaps because other phage or host products can partially compensate for their loss.

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1976-05-01
2021-10-18
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