1887

Abstract

SUMMARY

Two distinct types of rotavirus particle were isolated in caesium chloride density gradients. The higher density particle banded at 1µ38 g/ml and measured 55 ± 0µ4 nm in diameter while the less dense particle banded at 1µ36 g/ml, measured 66 ± 0µ4 nm in diameter and appeared to possess an extra outer capsid layer. Some forms intermediate between the two types were seen. Since the two particles had a similar but not identical morphology and polypeptide composition, they were considered to be different forms of the same virus. Infectivity was associated with the larger particle which contained one more polypeptide than the smaller particle.

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1976-05-01
2022-01-22
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