1887

Abstract

SUMMARY

With the exception of phage Qβ, the RNAs of all the other small icosahedral RNA viruses so far examined contain a poly (A) tract. This tract has been implicated in the infectivity of poliovirus RNA. We have now shown that Nodamura virus, a divided genome virus from which infective RNA can be extracted, does not contain any poly (A) tracts. This evidence with Nodamura virus shows that poly (A) is not a necessary requirement for the infectivity of virus RNA molecules.

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1976-01-01
2022-01-23
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References

  1. Armstrong I. A., Edmonds M., Nakazato H., Phillips B. S., Vaughan M. H. 1972; Polyadenylic add sequences in the virion RNA of poliovirus and Eastern equine encephalitis virus. Science, New York 176:526–528
    [Google Scholar]
  2. Brawerman O., Mendecki J., Lee S. Y. 1972; A procedure for the isolation of mammalian messenger ribonucleic acid. Biochemistry 11:637–641
    [Google Scholar]
  3. Brown F., Cartwright B. 1963; Purification of radioactive foot-and-mouth disease virus. Nature, London 199:1168–1170
    [Google Scholar]
  4. Davidson J. N., Smellie R. M. S. 1952; Phosphorus compounds in the cell. 3. The incorporation of radioactive phosphorus into the ribonucleotide fraction of liver tissue. Biochemical Journal 52:599–606
    [Google Scholar]
  5. Eaton B. T., Faulkner P. 1972; Heterogeneity in the poly (A) content of the genome of Sindbis virus. Virology 50:865–873
    [Google Scholar]
  6. El Manna M. M., Bruening G. 1973; Polyadenylate sequences in the ribonucleic acids of cowpea mosaic virus. Virology 56:198–206
    [Google Scholar]
  7. Nair C. N., Owens M. J. 1974; Preliminary observations pertaining to polyadenylation of rhinovirus RNA. Journal of Virology 13:535–537
    [Google Scholar]
  8. Newman J. F. E., Brown F. 1973; Evidence for a divided genome in Ncdamura virus, an anthropod-borne picornavirus. Journal of General Virology 21:371–384
    [Google Scholar]
  9. Plagemann P. G. W., Miller R. L. 1972; Purification of Mengo virus and identification of an A-rich segment in its ribonucleic acid. Journal of General Virology 17:349–353
    [Google Scholar]
  10. Rose J. K., Knipe D. 1975; Nucleotide sequence complexities, molecular weights, and poly (A) content of vesicular stomatitis virus mRNA species. Journal of Virology 15:994–1003
    [Google Scholar]
  11. Semancik J. S. 1974; Detection of polyadenylic acid sequences in plant pathogenic RNAs. Virology 62:288–291
    [Google Scholar]
  12. Spector D. H., Baltimore D. 1974; Requirement of 3′-terminal poly adenylic acid for the infectivity of poliovirus RNA. Proceedings of the National Academy of Sciences of the U iited States of America 71:2983–2987
    [Google Scholar]
  13. Weissmann C., Billeter M. A., Goodman H. M., Hindley J., Weber H. 1973; Structure and function of phage RNA. Annual Review of Biochemistry 42:303–328
    [Google Scholar]
  14. Yogo Y., Wimmer E. 1972; Polyadenylic acid at the 3′ terminus of poliovirus RNA. Proceedings of the National Academy of Sciences of the United States of America 69:1877–1882
    [Google Scholar]
  15. Yogo Y., Teng M. H., Wimmer E. 1974; Poly (U) in poliovirus minus RNA is 5′-terminal. Biochemical and Biophysical Research Communications 64:1101–1110
    [Google Scholar]
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