1887

Abstract

Summary

Heating high-titre preparations of reovirus particles for approximately 3 hr at temperatures of 52° to 53° converted the entire population to inner capsid components as monitored by electron microscopy. There was a tenfold loss in infectivity after this conversion. The residual infectivity could be accounted for only by the presence of the inner capsids, indicating that the outer layer of capsomeres is not mandatory for reovirus infectivity, but may be responsible for the stability of the complete virion.

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/content/journal/jgv/10.1099/0022-1317-3-2-233
1968-09-01
2021-10-16
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