A direct experimental comparison of the iridescent virus and the iridescent virus has shown them to be very similar but not identical. After extensive purification the viruses were differentiated by electrophoretic mobility, tryptic peptide patterns, serological cross-reactivity, and pathogenicity in a group of host insects. The viruses were identical in gross chemical composition and in a number of physical properties. A particle weight of 1.2 to 1.3 × 10 daltons was calculated by three methods. A slower sedimenting top component consisting of empty protein shells was found during the purification of each virus; similar empty shells could be produced by succinylation or formic acid-diphenylamine treatment of whole virus.


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