Influenza Virus RNA-synthesizing Complex in the Nucleoplasm of Infected Cells Free

Abstract

SUMMARY

An RNA-synthesizing complex was found in the nucleoplasm of fowl plague virus-infected chicken fibroblast and Ehrlich tumour cells. The complex sedimented at 120 S and banded in caesium chloride at 1.39 to 1.41 g/ml. It contained an influenza nucleocapsid protein as a major protein constituent. The complex functioned late in infection, and RNA synthesis in it was resistant to actinomycin D, the properties expected of influenza virus replicative complex.

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/content/journal/jgv/10.1099/0022-1317-29-1-137
1975-10-01
2024-03-28
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